2435-16-7

Basic information

• Product Name: 2-heptyltetrahydrofuran
• Synonyms: Furan, 2-heptyltetrahydro-; 2-Heptyl tetrahydrofuran; 2-Heptyl-tetrahydrofuran; 5-17-01-00162 (Beilstein Handbook Reference); BRN 0104446; Florane; 2-Heptyltetrahydrofuran; Furan, tetrahydro-2-heptyl-
• CAS NO: 2435-16-7
• Molecular Formula: C₁₁H₂₂O
• Molecular Weight: 170.2918
• EINECS: 219-423-9
• Mol File: 2435-16-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 217.9°C at 760 mmHg
• Flash Point: 73.9°C
• Density: 0.852g/cm³
• Vapor Pressure: 0.19mmHg at 25°C
• Refractive Index: 1.438
• CAS DataBase Reference: 2-heptyltetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-heptyltetrahydrofuran(2435-16-7)
• EPA Substance Registry System: 2-heptyltetrahydrofuran(2435-16-7)

Safety Data

• Hazardous Substances Data: 2435-16-7(Hazardous Substances Data)

Usage

General Description

2-Heptyltetrahydrofuran, also known as 2-methyl-5-propyltetrahydrofuran, is a chemical compound with the molecular formula C10H20O. It is a colorless liquid with a fruity odor, and it is commonly used as a solvent in various industrial applications. 2-Heptyltetrahydrofuran is also used as a reagent in organic synthesis and as a flavoring agent in food products. It has low toxicity and is considered to be relatively safe for handling, making it a versatile and useful compound in various fields.

Upstream product

• 112-43-6 10-Undecen-1-ol 
• 7664-93-9 sulfuric acid 
• 104-67-6 5-heptyldihydro-2(3H)-furanone 
• 108753-56-6 1-tetrahydro[2]furyl-heptan-4-ol 
• 110459-95-5 1-tetrahydro[2]furyl-heptan-4-one 

Downstream Products

• 110-15-6 succinic acid 

Relevant articles and documents

Lewis acid promoted ruthenium(II)-catalyzed etherifications by selective hydrogenation of carboxylic acids/esters

Ethers are of fundamental importance in organic chemistry and they are an integral part of valuable flavors, fragrances, and numerous bioactive compounds. In general, the reduction of esters constitutes the most straightforward preparation of ethers. Unfortunately, this transformation requires large amounts of metal hydrides. Presented herein is a bifunctional catalyst system, consisting of Ru/phosphine complex and aluminum triflate, which allows selective synthesis of ethers by hydrogenation of esters or carboxylic acids. Different lactones were reduced in good yields to the desired products. Even challenging aromatic and aliphatic esters were reduced to the desired products. Notably, the in situ formed catalyst can be reused several times without any significant loss of activity. An assist from Al: A bifunctional catalyst system consisting of a Ru/phosphine complex and aluminum triflate allows selective hydrogenation of esters to ethers. A variety of lactones were reduced to the desired products in good yields. The catalyst further provides a general method for the reduction of linear esters and reductive etherification of carboxylic acids with alcohols.