104-67-6Relevant articles and documents
Syntheses of rac- and optically active 2-alkyl-γ-butyrolactones and 2- alkyl-cyclobutanones
Krief, Alain,Ronvaux, Alain,Tuch, Arounarith
, p. 6903 - 6908 (1998)
γ-Butyrolactones have been produced in good yield from alkylidene cyclopropanes, as racemates or as an enantiomerically enriched mixture of stereoisomers (e.e.>60%) depending upon the method used. Optically active cyclobutanones which are intermediate in the process have been in some cases isolated. We show the limitations of a competitive method previously described and point out its weak step.
Tandem isomerization-lactonization of olefinic fatty acids using the Lewis acidic ionic liquid, choline chloride·2ZnCl2
Akula, Shivaraju,Kumar, Pandari Phani,Prasad, Rachapudi B.N.,Kanjilal, Sanjit
, p. 3471 - 3473 (2012)
The tandem isomerization-lactonization of unsaturated fatty acids to their corresponding γ-lactones was carried out for the first time in the presence of a Lewis acidic ionic liquid, choline chloride·2ZnCl 2. The ionic liquid initially catalyzes the stepwise migration of the double bond along the carbon chain toward the carboxyl group at the Δ4 position, which subsequently undergoes lactonization resulting in the formation of γ-lactones. This one step process allows the formation of γ-lactone in good yield with little or no formation of δ-lactones. The studied ionic liquid plays the dual role of solvent as well as catalyst.
Production method of synthesizing gamma-undecalactone synthetic perfume by reactive distillation
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Paragraph 0046-0070, (2019/01/08)
The invention belongs to the technical field of fine chemical production, and specifically relates to a production method of synthesizing gamma-undecalactone synthetic perfume by reactive distillation. The method includes the following steps: (a) mixing raw materials to obtain a mixture of ingredients; (b) discharging materials from an octanol elevated tank into a preheater for preheating; (c) pumping octanol into a high-boiling-point feed section of a reaction zone of a reactive distillation column, and pumping the mixture of ingredients into a low-boiling-point feed section of the reaction zone of the reactive distillation column; (d) separating out a crude product of gamma-undecalactone from the bottom of the reactive distillation column; (e) transferring the octanol separated in the step (d) to the preheater through a material pump to continue to participate in the reaction; and (f) further separating and purifying the crude product of gamma-undecalactone separated in the step (d).According to the production method provided by the present invention, a reactive distillation technology is adopted to timely separate by-product water, tert-butanol and low-boiling-point impuritiesproduced by a side reaction from the reaction system, so as to shorten the reaction time, improve the reaction speed and enhance the reaction efficiency.
Efficient synthesis of γ-lactones via gold-catalyzed tandem cycloisomerization/oxidation
Shu, Chao,Liu, Meng-Qi,Sun, Yu-Zhe,Ye, Long-Wu
, p. 4958 - 4961,4 (2012/12/12)
A novel Au-catalyzed tandem cycloisomerization/oxidation of homopropargyl alcohols was developed. Various γ-lactones can be accessed readily by utilizing this strategy. Notably, the mechanism of this reaction is distinctively different from the related Ru-catalyzed reactions where the ruthenium vinylidene intermediate was proposed.