2436-77-3Relevant academic research and scientific papers
Copper-Catalyzed Acetylation of Electron-Rich Phenols and Anilines
Zhang, Jieyu,Ke, Qiumin,Tian, Feitao,Jiang, Bei,Ji, Chang-An,Zhang, Lingling,Yu, Jian,Huang, Dayun,Yan, Guobing
supporting information, p. 726 - 730 (2019/03/26)
An approach has been developed for the copper-catalyzed acetylation of phenols and anilines with potassium thioacetate as an acetylating reagent. Although only electron-rich phenols and anilines are compatible with this protocol, the reaction can provide moderate to high yields under mild conditions. Compared with other acetylating reagents, the current reagent has certain advantages, such as its low cost, easy availability, stability, insensitivity to water or air, and ease of storage.
Transformation of N, N-Dimethylaniline N-Oxides into Diverse Tetrahydroquinoline Scaffolds via Formal Povarov Reactions
Bush, Timothy S.,Yap, Glenn P. A.,Chain, William J.
supporting information, p. 5406 - 5409 (2018/09/13)
A one-pot protocol for the assembly of diversely functionalized tetrahydro-, hexahydrofuro-, hexahydropyrano-, and tetrahydrobenzofuroquinolines from N,N-dimethylaniline N-oxides and various electron-rich olefins in a tandem Polonovski-Povarov sequence is reported. Following activation of the N-O bond with Boc2O, an exocyclic iminium ion is unveiled upon exposure to tin(IV) chloride. A formal inverse-electron-demand aza-Diels-Alder cyclization generates the tetrahydroquinoline core of 29 examples in up to 92% yield.
NON-SOLVENT SYSTEM ADHESIVE COMPOSITION FOR DENTISTRY
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Paragraph 0100, (2017/07/18)
PROBLEM TO BE SOLVED: To provide a non-solvent system adhesive composition for dentistry which exhibits excellent adhesiveness to any of dental enamel and dentin, and substantially contains neither water nor an organic solvent. SOLUTION: The invention provides a non-solvent system adhesive composition for dentistry containing neither water nor an organic solvent, wherein (A) a polymerizable monomer component,(B) aromatic amine having an electron withdrawing group, and(C) a polymerization initiator are contained; and the polymerizable monomer component (A) contains a phosphoric acid monomer (a1) having a phosphate acidic group (>P(=O)OH) and a sulfonic acid monomer (a2) having a sulfonic acid group at the following mass ratio; (a1):(a2)=98:2-67:33, and simultaneously contains the sulfonic acid monomer (a2) and the aromatic amine (B) at a ratio so that the molar ratio of an aromatic amino group and a sulfonic acid group (the aromatic amino group/sulfonic acid group) becomes 0.8 or more. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
Oxyaniliniums as acetylcholinesterase inhibitors for the reversal of neuromuscular block
Grove, Simon J.A.,Kaur, Jasmit,Muir, Alan W.,Pow, Eleanor,Tarver, Gary J.,Zhang, Ming-Qiang
, p. 193 - 196 (2007/10/03)
A series of oxyanilinium-based AChE inhibitors have been synthesised and tested for the reversal of vecuronium-induced neuromuscular block. Several compounds, for example 2-hydroxy- and 2-methoxy-N,N-dimethyl-N-allylanilinium bromide (3 and 6) showed comparable reversal potencies to edrophonium and clean in vivo cardiovascular profiles.
