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24365-47-7

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24365-47-7 Usage

General Description

Leupeptin is a potent reversible inhibitor of the proteolytic activity of lysosomal cysteine and serine proteases, as well as cathepsins B, H, and L. It is derived from Streptomyces exfoliatus and functions by forming a covalent bond with the active site of the protease. Leupeptin has been widely used in research for the inhibition of protein degradation and has potential applications in the treatment of certain lysosomal storage disorders and neurodegenerative diseases. It has also been studied for its immunomodulatory properties and potential anti-cancer effects. Additionally, leupeptin has shown promise in enhancing the stability and half-life of therapeutic proteins, making it a valuable tool in biotechnology and pharmaceutical research.

Check Digit Verification of cas no

The CAS Registry Mumber 24365-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,3,6 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 24365-47:
(7*2)+(6*4)+(5*3)+(4*6)+(3*5)+(2*4)+(1*7)=107
107 % 10 = 7
So 24365-47-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H38N6O4/c1-12(2)9-16(24-14(5)28)18(29)26-19(30)17(10-13(3)4)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17,25H,6-10H2,1-5H3,(H,24,28)(H4,21,22,23)(H,26,29,30)/t15?,16-,17-/m0/s1

24365-47-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name LEUPEPTIN

1.2 Other means of identification

Product number -
Other names acetyl-Leu-Leu-Arg-al

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24365-47-7 SDS

24365-47-7Downstream Products

24365-47-7Relevant articles and documents

Semisynthesis of 14C-labelled leupeptin

Saino,Someno,Miyazaki,Ishii

, p. 2319 - 2325 (2007/10/02)

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