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Leupeptin, a potent reversible inhibitor of lysosomal cysteine and serine proteases, including cathepsins B, H, and L, is derived from Streptomyces exfoliatus. It functions by forming a covalent bond with the active site of the protease, making it a valuable tool in research and potential therapeutic applications.

24365-47-7

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24365-47-7 Usage

Uses

Used in Research Applications:
Leupeptin is used as a research tool for the inhibition of protein degradation, aiding in the study of various biological processes and mechanisms.
Used in Pharmaceutical Industry:
Leupeptin is used as a potential therapeutic agent for the treatment of certain lysosomal storage disorders and neurodegenerative diseases, due to its ability to inhibit the proteolytic activity of lysosomal proteases.
Used in Immunomodulation:
Leupeptin is used as an immunomodulatory agent, with potential applications in modulating immune responses and treating immune-related conditions.
Used in Cancer Therapy:
Leupeptin is used as a potential anti-cancer agent, with studies suggesting its ability to modulate various oncological signaling pathways and exhibit synergistic effects when combined with conventional chemotherapeutic drugs.
Used in Biotechnology and Pharmaceutical Research:
Leupeptin is used as a stabilizing agent for therapeutic proteins, enhancing their stability and half-life, which is crucial for the development of effective protein-based drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 24365-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,3,6 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 24365-47:
(7*2)+(6*4)+(5*3)+(4*6)+(3*5)+(2*4)+(1*7)=107
107 % 10 = 7
So 24365-47-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H38N6O4/c1-12(2)9-16(24-14(5)28)18(29)26-19(30)17(10-13(3)4)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17,25H,6-10H2,1-5H3,(H,24,28)(H4,21,22,23)(H,26,29,30)/t15?,16-,17-/m0/s1

24365-47-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name LEUPEPTIN

1.2 Other means of identification

Product number -
Other names acetyl-Leu-Leu-Arg-al

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24365-47-7 SDS

24365-47-7Downstream Products

24365-47-7Relevant academic research and scientific papers

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