243665-60-3Relevant academic research and scientific papers
Synthesis of new thiazolo-celecoxib analogues as dual cyclooxygenase-2/15-lipoxygenase inhibitors: Determination of regio-specific different pyrazole cyclization by 2D NMR
Abdelall, Eman K.A.,Kamel, Gehan M.
, p. 250 - 258 (2016)
Two new series of 1,5-diaryl pyrazoles (5a, 5b, 7a, 7b and 10) and 1,5-diaryl pyrazoline (12a and 12b) were prepared as both Cyclooxygenase-2 and 15-lipoxygenase inhibitors. Carrageenan-induced rat paw edema, ulcer index and anti-COX-1/COX-2 and 15-LOX in
Synthesis and microbial activity of new thiazolyl 1,4-benzothiazines
Dengle,Ingle,Bondge,Mane
, p. 390 - 393 (2007/10/03)
5-Acyl-2-aryl-4-methyl thiazoles 1 have been converted to 1-(2'-aryl- 4'-methylthiazol-5'-yl)-3-aryl-2-propen-1-ones 2 by Claisen-Schmidt condensation. The chalcones 2 are brominated to give their bromo derivatives 3 which on hydrolysis yield 1-(2'-aryl-4
