243845-93-4

Upstream product

• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 243845-89-8 (4-bromo-phenyl)-(2-pyrrolidin-1-yl-benzo[b]thiophen-3-yl)-methanone 
• 243845-91-2 (4-bromo-phenyl)-(2-morpholin-4-yl-benzo[b]thiophen-3-yl)-methanone 
• 243845-90-1 (4-bromo-phenyl)-(2-piperidin-1-yl-benzo[b]thiophen-3-yl)-methanone 
• 5394-13-8 2-bromo-1-benzothiophene 
• 19983-26-7 2-(1-pyrrolidinyl)benzothiophene 
• 586-75-4 4-chlorobenzoyl chloride 
• 40584-57-4 2-(piperidin-1-yl)-1-benzothiophene 
• 18774-55-5 2-morpholinobenzothiophene 

Downstream Products

• 63676-08-4 2-(4-methoxyphenyl)benzo[b]thiophen-3-yl 4-[2-(1-piperidyl)ethoxy]phenyl ketone 

Relevant academic research and scientific papers

Synergistic methodologies for the synthesis of 3-aroyl-2- arylbenzo[b]thiophene-based selective estrogen receptor modulators. Two concise syntheses of raloxifene

Difunctionalized benzo[b]thiophene intermediates are prepared which allow fully independent elaboration of the 2-aryl position or the tether position of benzo[b]thiophene-based selective estrogen receptor modulators (SERMs). Two concise syntheses of the SERM raloxifene (Evista) are presented.