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CAS

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2439-37-4

L-Leucine, N,N-dimethyl-, with the molecular formula C8H18N2O2, is a derivative of the essential amino acid leucine. L-Leucine, N,N-dimethylis characterized by the presence of two methyl groups bonded to the nitrogen atom, which distinguishes it from the parent amino acid. Leucine plays a crucial role in protein synthesis and muscle repair within the body. The N,N-dimethyl modification of leucine may confer unique properties and potential applications in various fields, including pharmaceuticals, biotechnology, and research.

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  • 2439-37-4 Structure

  • Basic information

    1. Product Name: L-Leucine, N,N-dimethyl-
    2. Synonyms:
    3. CAS NO:2439-37-4
    4. Molecular Formula: C8H17NO2
    5. Molecular Weight: 159.228
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2439-37-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: L-Leucine, N,N-dimethyl-(CAS DataBase Reference)
    10. NIST Chemistry Reference: L-Leucine, N,N-dimethyl-(2439-37-4)
    11. EPA Substance Registry System: L-Leucine, N,N-dimethyl-(2439-37-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2439-37-4(Hazardous Substances Data)

2439-37-4 Usage

Uses

Used in Pharmaceutical Industry:
L-Leucine, N,N-dimethylis used as a building block for the development of new drugs or therapeutic agents. The N,N-dimethyl group may enhance the compound's stability, solubility, or bioavailability, making it a promising candidate for medicinal chemistry.
Used in Biotechnology Industry:
L-Leucine, N,N-dimethylis utilized in the creation of novel biotechnological products, such as modified proteins or enzymes with altered functions or improved properties. The N,N-dimethyl modification may provide insights into the structure-function relationships of proteins and contribute to the advancement of biotechnological applications.
Used in Biochemical and Molecular Biology Research:
L-Leucine, N,N-dimethylserves as a valuable research tool in the study of leucine's role in cellular processes. The modified compound can be used to investigate the mechanisms of protein synthesis, muscle repair, and other biological pathways, contributing to a deeper understanding of leucine's functions and potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 2439-37-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,3 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2439-37:
(6*2)+(5*4)+(4*3)+(3*9)+(2*3)+(1*7)=84
84 % 10 = 4
So 2439-37-4 is a valid CAS Registry Number.

2439-37-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-(dimethylamino)-4-methylpentanoic acid

1.2 Other means of identification

Product number -
Other names L-Leucine,N,N-dimethyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2439-37-4 SDS

2439-37-4Upstream product

2439-37-4Relevant articles and documents

Isolation and structure elucidation of cyclopeptide alkaloids from the leaves of Heisteria parvifolia

Bitchi, Michel Boni,Magid, Abdulmagid Alabdul,Kabran, Faustin Aka,Yao-Kouassi, Philomène Akoua,Harakat, Dominique,Morjani, Hamid,Tonzibo, Félix Zanahi,Voutquenne-Nazabadioko, Laurence

, (2019/08/12)

Heisteria parvifolia Sm. is prescribed in traditional medecine against numerous diseases in C?te d'Ivoire. Due to the shortcoming in scientifical knowledge of use of this species, our investigations revealed five undescribed cyclopeptide alkaloids added to one known derivative namely anorldianine. These compounds were elucidated by 1D and 2D-NMR experiments and comparison with literature data, and confirmed by HR-ESI-MS. Cytotoxic activity evaluation of these compounds against the chronic myeloid leukemia (K565) cell line exhibited an antiproliferative activity with cell growth inhibition from 13% to 46%.

Cyclopeptide alkaloids of Zizyphus xylopyra

Rai, Nisha,Singh, Sarita,Singh,Pandey

experimental part, p. 336 - 337 (2009/06/25)

14-Membered cyclopeptide alkaloids, franganine, frangufoline, amphibine-D and mauritine-A has been isolated from the whole plant of Zizyphus xylopyra and their structures established by spectral evidences. This is the first report of these alkaloids from Z. xylopyra.

Reduced dipeptide analogues as calcium channel antagonists

-

, (2008/06/13)

The present invention provides novel N-type calcium channel blockers, compositions comprising them, and methods of their use. The compounds of the invention are useful in the treatment of stroke, cerebral ischemia, pain, epilepsy, and head trauma. The nov

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