24391-41-1

Basic information

• Product Name: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
• Synonyms: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile;7H-Pyrrolo[2,3-d]pyriMidine-5-carbonitrile,4-chloro-;4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-5-carbonitrile
• CAS NO: 24391-41-1
• Molecular Formula: C₇H₃ClN₄
• Molecular Weight: 178.582
• EINECS: 200-258-5
• Product Categories: intermediates;Heterocycle-Pyrimidine series
• Mol File: 24391-41-1.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 235.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.61 g/cm³
• Refractive Index: 1.708
• PKA: 8.84±0.20(Predicted)
• CAS DataBase Reference: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile(24391-41-1)
• EPA Substance Registry System: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile(24391-41-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 24391-41-1(Hazardous Substances Data)

Usage

General Description

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, also known as CAS Number 84905-80-6, is a synthetic organic compound belonging to the class of pyrrolopyrimidines. It's a specific type of heterocyclic aromatic organic compound consisting of a pyrrole and a pyrimidine ring fused together. 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile is known for its high reactivity due to the presence of both the chloro-group and the carbonitrile group. Although it does not have much direct use, it serves as a valuable building block in the chemical industry, often used in the synthesis of more complex molecules especially in medical, pharmaceutical and agrochemical research. The exact physical features, including boiling point, melting point, and solubility can vary based on different factors. The compound normally appears as a white to light yellow crystalline powder.

InChI:InChI=1/C7H3ClN4/c8-6-5-4(1-9)2-10-7(5)12-3-11-6/h2-3H,(H,10,11,12)

Synthetic route

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde oxime (908287-23-0) → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
With thionyl chloride In dichloromethane at 20℃;	97%
With thionyl chloride In dichloromethane at 25 - 45℃;	89.4%
With thionyl chloride In dichloromethane at 20 - 40℃; for 22h;	77%
Stage #1: 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde oxime With thionyl chloride In dichloromethane at 20℃; Stage #2: With sodium hydrogencarbonate In water pH=4;
With thionyl chloride In dichloromethane at 20℃;

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde oxime → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
With thionyl chloride In dichloromethane at 20 - 45℃;	89.4%

5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine (22276-95-5) + 4-tolyl thiocyanate (5285-74-5) → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
With n-butyllithium In tetrahydrofuran; methanol; dichloromethane

4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (123148-78-7) + tri-n-butyltin cyanide (2179-92-2) → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
Stage #1: tri-n-butyltin cyanide; tetrakis(triphenylphosphine) palladium(0) In 1,1-dichloroethane for 0.5h; Inert atmosphere; Reflux; Stage #2: 4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine In 1,1-dichloroethane for 24h; Reflux; Inert atmosphere;

5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine (22276-95-5) → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
Multi-step reaction with 3 steps 1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere 1.2: -78 - 20 °C 2.1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 1 h / 20 °C 3.1: thionyl chloride / dichloromethane / 20 °C 3.2: pH 4 View Scheme
Multi-step reaction with 3 steps 1.1: n-butyllithium / tetrahydrofuran / 1.17 h / -78 °C / Inert atmosphere 1.2: -78 - 20 °C 2.1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 0.5 h / 20 °C 3.1: thionyl chloride / dichloromethane / 20 °C View Scheme
Multi-step reaction with 3 steps 1.1: n-butyllithium / tetrahydrofuran / 1.17 h / -78 °C / Inert atmosphere 1.2: -78 - 20 °C 2.1: hydroxylamine hydrochloride; sodium hydroxide / water; ethanol / 1 h / 20 °C 3.1: thionyl chloride / dichloromethane / 20 °C View Scheme

4-chloro-1H-pyrrolo[2,3-d]pyrimidine (3680-69-1) → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
Multi-step reaction with 4 steps 1.1: N-Bromosuccinimide / dichloromethane / 3 h / 20 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere 2.2: -78 - 20 °C 3.1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 1 h / 20 °C 4.1: thionyl chloride / dichloromethane / 20 °C 4.2: pH 4 View Scheme
Multi-step reaction with 4 steps 1.1: N-Bromosuccinimide / dichloromethane / 3 h / 20 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran / 1.17 h / -78 °C / Inert atmosphere 2.2: -78 - 20 °C 3.1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 0.5 h / 20 °C 4.1: thionyl chloride / dichloromethane / 20 °C View Scheme
Multi-step reaction with 2 steps 1.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 1 h / 20 °C 2.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere 2.2: -78 - 20 °C View Scheme
Multi-step reaction with 4 steps 1.1: N-Bromosuccinimide / dichloromethane / 3 h / 20 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran / 1.17 h / -78 °C / Inert atmosphere 2.2: -78 - 20 °C 3.1: hydroxylamine hydrochloride; sodium hydroxide / water; ethanol / 1 h / 20 °C 4.1: thionyl chloride / dichloromethane / 20 °C View Scheme
Multi-step reaction with 2 steps 1.1: N-iodo-succinimide / N,N-dimethyl-formamide / 20 °C 2.1: tetrakis(triphenylphosphine) palladium(0) / 1,1-dichloroethane / 0.5 h / Inert atmosphere; Reflux 2.2: 24 h / Reflux; Inert atmosphere View Scheme

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxaldehyde → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 1 h / 20 °C 2.1: thionyl chloride / dichloromethane / 20 °C 2.2: pH 4 View Scheme
Multi-step reaction with 2 steps 1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 0.5 h / 20 °C 2: thionyl chloride / dichloromethane / 20 °C View Scheme
Multi-step reaction with 2 steps 1: hydroxylamine hydrochloride; sodium hydroxide / water; ethanol / 1 h / 20 °C 2: thionyl chloride / dichloromethane / 20 °C View Scheme

5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine (22276-95-5) + P-toluenesulfonyl cyanide (19158-51-1) → 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1)

Conditions	Yield
Stage #1: 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere; Stage #2: P-toluenesulfonyl cyanide In tetrahydrofuran at -78 - 20℃;

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) + benzyl spiro[indoline-3,4’-piperidine]-1‘-carboxylate (167484-18-6) → benzyl 1-(5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxylate

Conditions	Yield
With potassium dihydrogenphosphate; phosphoric acid In dimethyl sulfoxide at 80℃; for 12h;	74%
With potassium dihydrogenphosphate; phosphoric acid In dimethyl sulfoxide at 80℃;

bromoacetic acid tert-butyl ester (5292-43-3) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → tert-butyl 2-(4-chloro-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-7-yl)acetate

Conditions	Yield
Stage #1: 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile With sodium hydride In N,N-dimethyl-formamide; mineral oil for 0.0833333h; Stage #2: bromoacetic acid tert-butyl ester In N,N-dimethyl-formamide; mineral oil for 2h;	74%

(S)-3-phenyl-2-(pyrrolidin-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4(3H)-one hydrochloride (1548339-56-5) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → (S)-4-(2-(4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (1548331-43-6)

Conditions	Yield
With triethylamine In butan-1-ol for 1.5h; Reflux;	64%
With triethylamine In butan-1-ol for 1.5h; Reflux;	64%
With triethylamine In butan-1-ol for 1.5h; Reflux;

(S)-2-(azetidin-2-yl)-5-chloro-3-(2,2-difluoroethyl)pyrrolo[1,2-f][1,2,4] triazin4(3H)-one hydrochloride (1548339-64-5) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → (S)-4-(2-(5-chloro-3-(2,2-difluoroethyl)-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)azetidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (1548333-77-2)

Conditions	Yield
With triethylamine In butan-1-ol at 130℃; for 2h;	63%
With triethylamine In butan-1-ol at 130℃; for 2h;	63%
With triethylamine In butan-1-ol at 130℃; for 2h;	63%

(5)-7-fluoro-2-(pyrrolidin-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4(3H)-one hydrochloride (1548341-37-2) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → (S)-4-(2-(7-fiuoro-4-oxo-3,4-dihydropyrrolo[1,2-f][l,2,4]triazin-2-yl)pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (1548335-65-4)

Conditions	Yield
With triethylamine In butan-1-ol for 2h; Reflux;	62%
With triethylamine In butan-1-ol for 2h; Reflux;	27 mg

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) + (3-hydroxymethyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester (475469-15-9) → [1-(5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-hydroxymethyl-pyrrolidin-3-yl]-carbamic acid tert-butyl ester (1004991-84-7)

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 80℃; for 5h;	60%

methanol (67-56-1) + carbon monoxide (201230-82-2) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → C9H6N4O2 (1095822-75-5)

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride at 100℃; under 5171.62 Torr; for 16h;	58%

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) + 4-sulfamoylphenylboronic acid (613660-87-0) → 4-(5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzenesulfonamide

Conditions	Yield
With dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); tert-butylamine In water; isopropyl alcohol at 160℃; for 1h; Inert atmosphere;	48%

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) + 1,2,3-tri-O-acetyl-5-O-benzoyl-5-(R)-C-methyl-β-D-ribofuranose (53872-91-6, 53872-94-9, 64761-44-0, 64761-45-1, 64761-46-2, 64761-47-3, 108836-00-6) → 4-chloro-5-cyano-7-(2',3'-di-O-acetyl-5'-O-benzoyl-5'(R)-C-methyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine (141232-12-4)

Conditions	Yield
With chloro-trimethyl-silane; trimethylsilyl trifluoromethanesulfonate; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile for 24h; Heating;	47%

piperidine (110-89-4) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → 4-Piperidin-1-yl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

Conditions	Yield
Stage #1: piperidine; 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile In tert-butyl alcohol for 2.5h; Heating / reflux; Stage #2: With hydrogenchloride In diethyl ether; water; tert-butyl alcohol Stage #3: With potassium hydroxide In water pH=7;	42%
In tert-butyl alcohol	29 mg (42%)

(S)-7-fluoro-3-isobutyl-2-(pyrrolidin-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4(3H)-one hydrochloride (1548341-44-1) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → (S)-4-(2-(7-fluoro-3-isobutyl-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (1548335-67-6)

Conditions	Yield
With triethylamine In butan-1-ol for 2h; Reflux;	31%
With triethylamine In butan-1-ol for 2h; Reflux;	31%
With triethylamine In butan-1-ol for 2h; Reflux;	31%

1,2,3-tri-O-acetyl-5-O-benzoyl-3-C-methyl-α-D-ribofuranose (60374-77-8, 80581-75-5, 89195-77-7, 115269-09-5, 115269-10-8) + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → 4-chloro-5-cyano-7-(2',3'-di-O-acetyl-5'-O-benzoyl-3'-C-methyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine (141232-11-3)

Conditions	Yield
With chloro-trimethyl-silane; trimethylsilyl trifluoromethanesulfonate; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile for 24h; Heating;	28%

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) + (1r,4r)-4-(dimethylamino)cyclohexan-1-ol → 4-[[4-(dimethylamino)cyclohexyl]oxyl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (1534374-53-2)

Conditions	Yield
Stage #1: (1r,4r)-4-(dimethylamino)cyclohexan-1-ol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Stage #2: 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile In tetrahydrofuran; mineral oil at 0℃; Reflux;	19%

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → Vengicide (606-58-6)

Conditions	Yield
Multi-step reaction with 2 steps 1: 31 percent / 1,1,1,3,3,3-hexamethyldisilazane (HMDS), trimethylsilyl chloride (TMSCl), trimethylsilyl triflate (TMSOTf) / acetonitrile / 24 h / Heating 2: 53 percent / methanol. NH3 / 8 h / 110 °C View Scheme

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → 4-amino-5-cyano-7-(3'-C-methyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine (141232-14-6)

Conditions	Yield
Multi-step reaction with 2 steps 1: 28 percent / 1,1,1,3,3,3-hexamethyldisilazane (HMDS), trimethylsilyl chloride (TMSCl), trimethylsilyl triflate (TMSOTf) / acetonitrile / 24 h / Heating 2: 51 percent / methanol. NH3 / 8 h / 110 °C View Scheme

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → 3'-C-methylsangivamycin (139209-27-1)

Conditions	Yield
Multi-step reaction with 3 steps 1: 28 percent / 1,1,1,3,3,3-hexamethyldisilazane (HMDS), trimethylsilyl chloride (TMSCl), trimethylsilyl triflate (TMSOTf) / acetonitrile / 24 h / Heating 2: 51 percent / methanol. NH3 / 8 h / 110 °C 3: 90 percent / 35percent aq. H2O2, conc. NH4OH / 1 h / Ambient temperature View Scheme

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → 5'(S)-C-methylsangivamycin (139209-29-3)

Conditions	Yield
Multi-step reaction with 3 steps 1: 32 percent / 1,1,1,3,3,3-hexamethyldisilazane (HMDS), trimethylsilyl chloride (TMSCl), trimethylsilyl triflate (TMSOTf) / acetonitrile / 24 h / Heating 2: 55 percent / methanol. NH3 / 8 h / 110 °C 3: 100 percent / 35percent aq. H2O2, conc. NH4OH / 1 h / Ambient temperature View Scheme

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → 4-amino-5-cyano-7-(5'(S)-C-methyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine (141232-16-8)

Conditions	Yield
Multi-step reaction with 2 steps 1: 32 percent / 1,1,1,3,3,3-hexamethyldisilazane (HMDS), trimethylsilyl chloride (TMSCl), trimethylsilyl triflate (TMSOTf) / acetonitrile / 24 h / Heating 2: 55 percent / methanol. NH3 / 8 h / 110 °C View Scheme

4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → sangivamycin (18417-89-5)

Conditions	Yield
Multi-step reaction with 3 steps 1: 31 percent / 1,1,1,3,3,3-hexamethyldisilazane (HMDS), trimethylsilyl chloride (TMSCl), trimethylsilyl triflate (TMSOTf) / acetonitrile / 24 h / Heating 2: 53 percent / methanol. NH3 / 8 h / 110 °C 3: 87 percent / 35percent aq. H2O2, conc. NH4OH / 1 h / Ambient temperature View Scheme

(R)-N-((3-aminopyrrolidin-3-yl)methyl)-2,4-difluorobenzamide + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → (S)-N-((3-amino-1-(5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)methyl)-2,4-difluorobenzamide

Conditions	Yield
With sodium hydrogencarbonate for 10h; Reflux;

C12H16FN3O + 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (24391-41-1) → (S)-N-((3-amino-1-(5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)methyl)-4-fluorobenzamide

Conditions	Yield
With sodium hydrogencarbonate for 10h; Reflux;

Upstream product

• 22276-95-5 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 123148-78-7 4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine 
• 2179-92-2 tri-n-butyltin cyanide 
• 5285-74-5 4-tolyl thiocyanate 
• 908287-23-0 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde oxime 

Downstream Products

• 1548332-49-5 (S)-4-(2-(5-chloro-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 1548332-62-2 (S)-4-(2-(5-chloro-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)azetidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 1548334-22-0 4-((2S,4S)-2-(5-chloro-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-fluoropyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 1548331-43-6 (S)-4-(2-(4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 18417-89-5 sangivamycin 
• 606-58-6 Vengicide 
• 141232-12-4 4-chloro-5-cyano-7-(2',3'-di-O-acetyl-5'-O-benzoyl-5'(R)-C-methyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine 
• 141232-13-5 4-chloro-5-cyano-7-(2',3'-di-O-acetyl-5'-O-benzoyl-5'(S)-C-methyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine 
• 141232-11-3 4-chloro-5-cyano-7-(2',3'-di-O-acetyl-5'-O-benzoyl-3'-C-methyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine 

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