244181-98-4Relevant academic research and scientific papers
Gated Migration for Enantioselective Synthesis of Palladium Allyls Using a PdHBr Synthon
Albéniz, Ana C.,Espinet, Pablo,Lin, Yong-Shou,Martín-Ruiz, Blanca
, p. 3359 - 3363 (2008/10/08)
The synthesis of enantiomerically pure palladium cyclic allyl complexes is accomplished by reaction of PdHBr with several chiral cyclic terpenes. The strategy used involves a 100% stereoselective Pd-migration from an attached chain to the ring through a chiral carbon ( gated migration ). PdHBr species are produced by β-H elimination in the benzylic moiety of [Pd2(μBr)2(η3-PfCH2CHPh) 2] (1, Pf = C6F5). The allylic complexes prepared are transformed by carbonylation reactions into chiral unsaturated methyl esters.
