244219-96-3

Basic information

• Product Name: 1,7-Isoquinolinediamine(9CI)
• Synonyms: 1,7-Isoquinolinediamine(9CI);1,7-IsoquinolinediaMine
• CAS NO: 244219-96-3
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.19
• Product Categories: ISOQUINOLINE
• Mol File: 244219-96-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,7-Isoquinolinediamine(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-Isoquinolinediamine(9CI)(244219-96-3)
• EPA Substance Registry System: 1,7-Isoquinolinediamine(9CI)(244219-96-3)

Safety Data

• Hazardous Substances Data: 244219-96-3(Hazardous Substances Data)

Usage

Chemical compound

A chemical compound with the molecular formula C9H9N3.

Derivative

A derivative of isoquinoline.

Pharmaceutical industry

Has potential use in the pharmaceutical industry.

Antineoplastic agent

Potential use as an antineoplastic agent.

Topoisomerase inhibitor

Potential use as a topoisomerase inhibitor.

Anti-cancer properties

Has been studied for its potential anti-cancer properties.

Inhibiting cancer cell growth

Has shown promise in inhibiting the growth of certain cancer cells.

Other medical conditions

Investigated for its potential role in treating other medical conditions such as inflammation and neurodegenerative diseases.

Further research

More research is needed to fully understand the potential uses and mechanisms of action of 1,7-Isoquinolinediamine(9CI).

Upstream product

• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 99365-69-2 7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride 
• 42923-79-5 7-nitro-1,2,3,4-tetrahydroisoquinoline 
• 13058-73-6 7-nitroisoquinoline 
• 244219-94-1 1-chloro-7-nitro-isoquinoline 
• 98410-85-6 1-Amino-7-nitroisoquinoline 

Downstream Products

• 943960-91-6 7-(3'-bromobenzylamino)-1-isoquinolinamine 
• 943960-90-5 7-(4'-chlorobenzylamino)-1-isoquinolinamine 
• 943960-88-1 7-benzylamino-1-isoquinolinamine 
• 943960-89-2 7-(3'-chlorobenzylamino)-1-isoquinolinamine 
• 943960-92-7 7-(3',4'-dichlorobenzylamino)-1-isoquinolinamine 

Relevant articles and documents

Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR

Basic molecular building blocks such as benzene rings, amidines, guanidines, and amino groups have been combined in a systematic way to generate ligand candidates for HIV-1 TAR RNA. Ranking of the resulting compounds was achieved in a fluorimetric Tat-TAR

In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones

A series of 1,7-diaminoisoquinolinamines, that are expected to mediate antimalarial activity by the same mechanism employed by the chalcones, were produced. Six 7-benzylamino-1-isoquinolinamines were found to be submicromolar inhibitors in vitro of drug-r

Synthesis and antimalarial activity of 7-benzylamino-1-isoquinolinamines

(Chemical Equation Presented) Computer modelling suggests that 7-benzylamino-1-isoquinolinamines should mediate antimalarial effects by a mechanism distinct from that employed by existing antimalarial drugs. A series of these compounds was prepared in sev

Amide derivatives and nociceptin antagonists

The present invention relates to a compound of the formula [1′] wherein R2is lower alkyl optionally substituted by hydroxy, amino and the like, ring B is phenyl, thienyl and the like, E is a single bond, —O—, —S— and the like, ring G is aryl, heterocyclic group and the like, R5is halogen atom, hydroxy, lower alkyl optionally substituted by halogen atom etc., and the like, t is 0 or an integer of 1 to 5, when t is an integer of 2 to 5, each R5may be the same or different, m is 0 or an integer of 1 to 8, and n is 0 or an integer of 1 to 4, and a nociceptin antagonist containing compound [1′] as an active ingredient. The compound [1′] shows, due to nociceptin antagonistic action, analgesic effect against sharp pain such as postoperative pain and the like. The present invention also relates to the use of certain amide derivative inclusive of compound [1′] as a nociceptin antagonist or analgesic.