24422-55-7

Upstream product

• 124-40-3 dimethyl amine 
• 2096-78-8 vinyldiphenylphosphine oxide 
• 24630-80-6 diphenylphosphine oxide 
• 23901-68-0 diphenyl(2-phenoxyethyl)phosphine oxide 
• 13683-01-7 Diphenylphosphonigsaeure-trimethylsilylester 
• 1499-21-4 Diphenylphosphinic chloride 
• 29679-67-2 N,N-dimethyl-2-diphenylphosphinoethylamine 

Downstream Products

• 111792-53-1 [Co(P(C₆H₅)2(O)C₂H₄N(CH₃)2)2(SCN)2] 
• 111812-01-2 [CoCl₃(P(C₆H₅)2(O)C₂H₄NH(CH₃)2)] 
• 111792-52-0 [NiCl₃(P(C₆H₅)2(O)C₂H₄NH(CH₃)2)] 

Relevant academic research and scientific papers

Crystal and molecular structure of [(C6H5)2P(=O)(CH2CH 2N(CH3)3)+][I-]

The title compound crystallizes in the centrosymmetric triclinic space group Pl with Z = 4. The crystallographic asymmetric unit contains two independent cations; interatomic distances within these include P=O = 1.47(1) and 1.47(1)?, P-C6H

2-Phenoxyethyldiphenylphosphine oxide as an equivalent of diphenylvinylphosphine oxide in nucleophilic additions

A facile method for the synthesis of β-functionalized ethyldiphenylphosphine oxides is developed based on readily available 2-phenoxyethyldiphenylphosphine oxide used as an equivalent of diphenylvinylphosphine oxide in the reactions of addition of different PH- and NH-nucleophiles in DMSO in the presence of KOH. The transformations of labile phosphine oxides of a general formula Ph2P(O)CH2CH2OR, where R = Ph, H, or Ph2P(O)CH = CH2, in aq.KOH/DMSO and solid KOH/DMSO systems are explored in the absence of nucleophilic reagents.

A practical and efficient green synthesis of β-aminophosphoryl compounds via the aza-Michael reaction in water

Biphasic systems room temperature imidazolium ionic liquid (RTIL)/water or water as a solvent significantly accelerate the addition of amines to vinylphosphoryl compounds hence opening green and effective synthesis of β-aminophosphoryl compounds in excellent yields over short reaction times. The application of water, being the cheapest and most non-toxic solvent, without any catalyst or co-solvent, is more advantageous as it provides a simple isolation procedure for products having high purity (> 95% according to the NMR data) via simple freeze-drying and does not require extraction with organic solvents. The solubility of the starting phosphorus substrate in water does not play crucial role in the reaction as it was demonstrated using water insoluble diphenylvinylphosphine oxide. In contrast to typical procedures, using a reactant ratio (vinylphosphoryl compound: amine) of 2:1 readily resulted in double phosphorylation of primary amines, including polyamines, in water.