Ethanamine, 2-(diphenylphosphinyl)-n,n-dimethyl-

Base Information

• Chemical Name: Ethanamine, 2-(diphenylphosphinyl)-n,n-dimethyl-
• CAS No.: 24422-55-7
• Molecular Formula: C16H20NOP
• Molecular Weight: 273.315
• DSSTox Substance ID: DTXSID30355338
• Wikidata: Q82134165
• ChEMBL ID: CHEMBL1503898
• Mol file: 24422-55-7.mol

Synonyms:24422-55-7;2-(diphenylphosphoryl)-N,N-dimethylethanamine;(2-(Dimethylamino)ethyl)diphenylphosphine oxide;ethanamine, 2-(diphenylphosphinyl)-n,n-dimethyl-;MLS001018554;CHEMBL1503898;DTXSID30355338;HMS1578O09;HMS2625L08;STK367028;AKOS001035659;SMR000354847;SR-01000196011;SR-01000196011-1;5116-02-9

Chemical Property of Ethanamine, 2-(diphenylphosphinyl)-n,n-dimethyl-

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 273.128251259
• Heavy Atom Count: 19
• Complexity: 282

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCP(=O)(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Ethanamine, 2-(diphenylphosphinyl)-n,n-dimethyl-

There total 7 articles about Ethanamine, 2-(diphenylphosphinyl)-n,n-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,N-dimethyl-2-diphenylphosphinoethylamine (29679-67-2) → P-(N,N-dimethylaminoethyl)-P,P-diphenylphosphine oxide (24422-55-7)

Guidance literature:

With dihydrogen peroxide; In acetone; for 1h; Heating;

DOI:10.1007/bf01664651

Reference yield: 80.0%

diphenyl(2-phenoxyethyl)phosphine oxide (23901-68-0) + dimethyl amine (124-40-3) → P-(N,N-dimethylaminoethyl)-P,P-diphenylphosphine oxide (24422-55-7)

Guidance literature:

With potassium hydroxide; In water; dimethyl sulfoxide; at 70 ℃; for 2.5h;

DOI:10.1080/10426507.2021.1939346

Reference yield:

dimethyl amine (124-40-3) + vinyldiphenylphosphine oxide (2096-78-8) → P-(N,N-dimethylaminoethyl)-P,P-diphenylphosphine oxide (24422-55-7)

Guidance literature:

upstream raw materials:

dimethyl amine

vinyldiphenylphosphine oxide

N,N-dimethyl-2-diphenylphosphinoethylamine

Diphenylphosphinic chloride

Downstream raw materials:

[NiCl₃(P(C₆H₅)2(O)C₂H₄NH(CH₃)2)]

[CoCl₃(P(C₆H₅)2(O)C₂H₄NH(CH₃)2)]

[Co(P(C₆H₅)2(O)C₂H₄N(CH₃)2)2(SCN)2]