244263-56-7

Basic information

• Product Name: trans-(1R,4S)(+)-N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl]-N-methyl formamide
• Synonyms: trans-(1R,4S)(+)-N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl]-N-methyl formamide
• CAS NO: 244263-56-7
• Molecular Weight: 334.245
• Mol File: 244263-56-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-(1R,4S)(+)-N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl]-N-methyl formamide(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(1R,4S)(+)-N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl]-N-methyl formamide(244263-56-7)
• EPA Substance Registry System: trans-(1R,4S)(+)-N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl]-N-methyl formamide(244263-56-7)

Safety Data

• Hazardous Substances Data: 244263-56-7(Hazardous Substances Data)

Upstream product

• 123-39-7 N-Methylformamide 
• 593-51-1 methylamine hydrochloride 
• 79560-19-3 4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one 

Downstream Products

• 329009-20-3 trans-(1R,4S)(+)-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine hydrochloride 
• 79617-89-3 cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthaleneamine hydrochloride 

Relevant articles and documents

PROCESS FOR THE MANUFACTURE OF SERTRALINE

Process for the preparation of sertraline by reductive amination of racemic 4-(3, 4-dichlorophenyl)-3, 4-dihydro-1-(2H)-naphthalenone, carried out as one- reaction-vessel process without isolation of intermediates, in the form of pure separated cis and trans isomers, the way of conversion of trans isomer to cis isomer and preparation of FII polymorph of 1S-cis isomer from any other polymorph.