244266-70-4

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 2129-89-7 diphenyl(methyl)phosphine oxide 

Downstream Products

• 59675-60-4 (E)-[2-(4-methoxyphenylvinyl)]diphenylphosphane oxide 
• 203574-99-6 (1R,1'R)-N-benzyl-N-[1'-methylbenzyl]-2-diphenylphosphinoyl-1-(p-methoxyphenyl)ethylamine 
• 452096-42-3 (R)-2-(Diphenyl-phosphinoyl)-1-(4-methoxy-phenyl)-ethylamine 

Relevant academic research and scientific papers

Diastereoselective nucleophilic additions to vinyl phosphine oxides

Some hydrogen, carbon, silicon, sulfur, nitrogen and oxygen nucleophiles react diastereoselectively with γ-oxygenated chiral vinyl phosphine oxides to give β-substituted phosphine oxides. Lithium N-benzyl-α-methylbenzylamide adds to prochiral vinyl phosphine oxides in the presence of trimethylsilyl chloride to provide, after protodesilylation, β-amino phosphine oxides as single diastereoisomers.