24457-21-4

Basic information

• Product Name: TERT-BUTYL 2-BROMOBUTYRATE
• Synonyms: TERT-BUTYL 2-BROMOBUTYRATE;2-Bromobutyric acid tert-butyl ester;2-Bromoisobutyricacid t-butylether;tert-Butyl2-bromobutyrate,98%;tert-Butyl 2-bromobutanoate
• CAS NO: 24457-21-4
• Molecular Formula: C₈H₁₅BrO₂
• Molecular Weight: 223.11
• Mol File: 24457-21-4.mol

Chemical Properties

• Boiling Point: 72-76°C 12mm
• Flash Point: 72-76°C/12mm
• Appearance: /
• Density: 1,2 g/cm3
• Vapor Pressure: 0.614mmHg at 25°C
• Refractive Index: 1.4410
• BRN: 2040298
• CAS DataBase Reference: TERT-BUTYL 2-BROMOBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 2-BROMOBUTYRATE(24457-21-4)
• EPA Substance Registry System: TERT-BUTYL 2-BROMOBUTYRATE(24457-21-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3334
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 24457-21-4(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
TERT-BUTYL 2-BROMOBUTYRATE is used as a chemical intermediate for various chemical syntheses, contributing to the production of a range of compounds.
Used in Pharmaceutical Manufacturing:
TERT-BUTYL 2-BROMOBUTYRATE is used as a chemical intermediate in the pharmaceutical industry, playing a crucial role in the synthesis of certain drugs.
Safety Precautions:
Due to its biochemical properties, TERT-BUTYL 2-BROMOBUTYRATE can cause irritation to eyes, skin, and the respiratory system if improperly handled. It is essential to store the chemical under controlled conditions to avoid its reaction with oxidizing agents.

InChI:InChI=1/C8H15BrO2/c1-5-6(9)7(10)11-8(2,3)4/h6H,5H2,1-4H3

Upstream product

• 1694-31-1 tert-butyl acetoacetate 
• 75-03-6 ethyl iodide 
• 540-88-5 acetic acid tert-butyl ester 
• 80-58-0 2-Bromobutyric acid 
• 26074-52-2 2-bromo-butyryl bromide 
• 75-65-0 tert-butyl alcohol 
• 115-11-7 isobutene 

Downstream Products

• 1429383-97-0 (R)-tert-butyl 2-((2R,3R,6R)-2-(3-chlorophenyl)-3-(4-chlorophenyl)-6-(2-methoxy-2-oxoethyl)-5-oxomorpholino)butanoate 
• 1429383-98-1 (R)-tert-butyl 2-((2R,3R,6S)-2-(3-chlorophenyl)-3-(4-chlorophenyl)-6-(2-methoxy-2-oxoethyl)-5-oxomorpholino)butanoate 
• 1429383-99-2 (S)-tert-butyl 2-((2R,3R,6R)-2-(3-chlorophenyl)-3-(4-chlorophenyl)-6-(2-methoxy-2-oxoethyl)-5-oxomorpholino)butanoate 

Relevant articles and documents

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Cephalosporin compounds represented by the general formula STR1 wherein R represents a group shown by formula STR2 wherein R1 represents a hydrogen atom or a lower alkyl group of 1-3 carbon atoms and R2 represents a hydrogen atom, a lower alkyl group of 1-3 carbon atoms, a phenyl group which may be substituted by an amino or hydroxy group, a cyano group, a carboxy group, or a carboxymethyl group; said R1 and R2 may form a cycloalkylidene group of 4-6 carbon atoms together with the carbon atom to which they are bonded) or a group shown by formula --CH2 --R3 (wherein R3 represents a hydrogen atom, a halogenomethyl group, a carbamoyl group, a carboxymethyl group, α4-carboxy-3-hydroxyisothiazol-5-yl-thiomethyl group, or α2-carboxyphenylthiomethyl group); R' represents a group shown by formula STR3 (wherein Ra represents a carboxy group, a cyano group, or a carbamoyl group which may be substituted by a lower alkyl group of 1-3 carbon atoms and Rb represents a hydrogen atom or an amino group) or a group shown by formula STR4 (wherein Ra and Rb have the same significance as above); and the waveline ? shows an anti-form or syn-form bond and the salts thereof. They possess excellent antibacterial activities against gram positive bacteria and gram negative bacteria, in particular, pseudomonas aeruginosa and are useful as anti-bacterial agents.