244624-98-4

Upstream product

• 6285-05-8 4'-chloropropiophenone 
• 68-12-2 N,N-dimethyl-formamide 
• 536-74-3 phenylacetylene 
• 173848-70-9 (Z)-3-bromo-2-methyl-3-phenylprop-2-en-1-al 
• 93-55-0 1-phenyl-propan-1-one 

Downstream Products

• 1330631-20-3 (Z)-4,6-dimethyl-1,3-diphenylhepta-3,5-dien-1-yne 

Relevant academic research and scientific papers

Gold(I)-catalyzed tandem cyclization-selective migration reaction of 1,3-dien-5-ynes: Regioselective synthesis of highly substituted benzenes

Highly substituted benzene derivatives have been easily prepared in a regioselective way from readily available 1,3-hexadien-5-ynes through a gold(I)-catalyzed tandem reaction. The process involves an initial cyclization followed by a selective Wagner-Meerwein shift in which the migration preference seems to be determined by the ability to stabilize a positive charge.

Synthesis and stereochemistry of β-aryl-β-haloacroleins: Useful intermediates for the preparation of (Z) and (E)-2-en-4-ynecarbaldehydes and for the synthesis of rubrolides

The synthesis of α-substituted β-aryl-β-haloacroleins by two different pathways is presented. The determination of their stereochemistry by NOE experiments is reported for the first time. Furthermore, we describe the preparation of 2-en-4-ynecarbaldehydes