24468-88-0

Basic information

• Product Name: N-Benzyl-2-broMo-N-(2-broMoethyl)ethanaMine
• Synonyms: N-Benzyl-2-broMo-N-(2-broMoethyl)ethanaMine;N,N-Bis(2-bromoethyl)benzylamine
• CAS NO: 24468-88-0
• Molecular Formula: C₁₁H₁₅Br₂N
• Molecular Weight: 321.0515
• Mol File: 24468-88-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 319.4°C at 760 mmHg
• Flash Point: 147°C
• Appearance: /
• Density: 1.563g/cm³
• Vapor Pressure: 0.000339mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 5.63±0.50(Predicted)
• CAS DataBase Reference: N-Benzyl-2-broMo-N-(2-broMoethyl)ethanaMine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzyl-2-broMo-N-(2-broMoethyl)ethanaMine(24468-88-0)
• EPA Substance Registry System: N-Benzyl-2-broMo-N-(2-broMoethyl)ethanaMine(24468-88-0)

Safety Data

• Hazardous Substances Data: 24468-88-0(Hazardous Substances Data)

Usage

General Description

N-Benzyl-2-bromo-N-(2-bromoethyl)ethanamine is a chemical compound with the molecular formula C10H13Br2N. It is commonly used in organic synthesis and pharmaceutical research. N-Benzyl-2-broMo-N-(2-broMoethyl)ethanaMine is classified as an amine, containing both benzyl and bromoethyl functional groups. It is primarily utilized as an intermediate in the production of various pharmaceuticals and organic compounds. Additionally, it is known to possess certain pharmacological properties, making it a subject of interest in drug discovery and development. Due to its bromo substituents, it presents potential reactivity in various chemical reactions, making it highly useful in synthetic chemistry. Overall, N-Benzyl-2-bromo-N-(2-bromoethyl)ethanamine is a versatile and important chemical compound with diverse applications in the field of organic chemistry and pharmaceutical research.

InChI:InChI=1/C11H15Br2N/c12-6-8-14(9-7-13)10-11-4-2-1-3-5-11/h1-5H,6-10H2

Upstream product

• 100-39-0 benzyl bromide 
• 101-32-6 N-benzyl-diethanolamine 
• 98-88-4 benzoyl chloride 
• 91335-65-8 N,N-bis-(2-bromo-ethyl)-benzamide 

Downstream Products

• 99573-07-6 N,N-bis(2-(diphenylphosphino)ethyl)benzylamine 
• 1419389-16-4 C₂₂H₂₅NO₃ 
• 1419389-20-0 C₂₂H₁₉F₆NO₇S₂ 

Relevant articles and documents

Compound serving as SHP2 inhibitor and application thereof

The invention belongs to the field of medical chemistry, relates to a compound serving as an SHP2 inhibitor and an application of the compound, and particularly provides a compound shown in a formula (I) or an isomer, pharmaceutically acceptable salt, solvate, crystal or prodrug of the compound, processes for the preparation, pharmaceutical compositions containing these compounds and the use of these compounds or compositions for the treatment of SHP2 mediated diseases.

IMIDAZOPYRIMIDINE DERIVATIVES

The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating cancers.

Pyrazinothiazole compound and application thereof, and pharmaceutical composition containing pyrazinothiazole compound

The invention discloses a pyrazinothiazole compound, an application of the pyrazinothiazole compound, and a pharmaceutical composition containing the pyrazinothiazole compound, and provides a pyrazinothiazole compound represented by a formula A or a pharmaceutically acceptable salt of the pyrazinothiazole compound. The pyrazinothiazole compound provided by the invention has relatively good SHP2 inhibitory activity.