24484-99-9

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2,3-Diamino-4,6-dichloropyridine is used as a building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of new compounds with potential therapeutic and pesticidal properties.
Used in Corrosion Inhibition:
2,3-Diamino-4,6-dichloropyridine has been studied for its potential application as a corrosion inhibitor for metal surfaces. The presence of amino and chlorine atoms in its structure may contribute to its ability to protect metal surfaces from corrosion, making it a candidate for use in industrial applications to prolong the lifespan of metal equipment and structures.

Upstream product

• 116632-24-7 2-amino-4,6-dichloropyridine 
• 37660-64-3 2-amino-4,6-dichloro-3-nitropyridine 

Downstream Products

• 1283075-60-4 6,8-dichloropyrido[2,3-b]pyrazine 
• 1398056-96-6 [6-(2-fluoro-phenyl)-pyrido[2,3-b]pyrazin-8-yl]-pyridin-4-yl-amine 
• 1398057-31-2 [6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-boronic acid 
• 1398057-34-5 6-(2-fluoro-phenyl)-8-(6-oxy-[2,6]naphthyridin-1-yl)-pyrido[2,3-b]pyrazine 
• 1398056-99-9 5-[6-(2-fluoro-phenyl)-pyrido[2,3-b]pyrazin-8-yl]-[2,6]naphthyridin-1-ylamine 
• 1398057-10-7 C₂₀H₁₂FN₅ 
• 1398057-18-5 6-(2-fluoro-phenyl)-8-[5-(1-methyl-1H-pyrazol-4-yl)-pyridin-3-yl]-pyrido[2,3-b]pyrazine 
• 1398057-36-7 4-(4-{5-[6-(2-fluoro-phenyl)-pyrido[2,3-b]pyrazin-8-yl]-pyridin-3-yl}-pyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1398057-16-3 6-(2-fluoro-phenyl)-8-{5-[1-(1-methyl-piperidin-4-yl)-1H-pyrazol-4-yl]-pyridin-3-yl}-pyrido[2,3-b]pyrazine 
• 1398057-29-8 8-chloro-6-(2-fluoro-phenyl)-pyrido[2,3-b]pyrazine 
• 4228-88-0 4,6-Dichlor-2-trifluormethyl-benzimidazol 

Relevant academic research and scientific papers

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

2-(HETERO)ARYL-BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF ASPARAGIME EMETHYL TRANSFERASE

Substituted benzimidazole and 3H-imidazo[4,5-b]pyridines or formula I: where X and Y respectively are selected from: (i) N and N; and (ii) N and CR4; A2 is selected from:, a C5 heteroarylene group, containing 2 or 3 ring heteroatoms, where the bonds to L1 and the core are β to one another; L1 is selected from: (i)A1-O-CH2-A2; (ii)A1-CH2-O-A2; (iii)A1-C(=O)-NH-A2; (iv)A1-CH(OH)-A2; (v)A1-CH2-NH-C(=O)-A2; (vi) A1-S-CH2-A2; (vii)A1- CH2-S-A2; (viii)A1-CH2-A2; and (ix)A1-CH(CH3)-O-A2; A1 is phenyl, optionally substituted by F or CF3; their use as pharmaceuticals, and in particular, in treating cancer and hemoglobinopathies.