24490-79-7

Basic information

• Product Name: 2-Propenenitrile,3-(4-pyridinyl)-(9CI)
• Synonyms: 2-Propenenitrile,3-(4-pyridinyl)-(9CI);3-(Pyridin-4-yl)acrylonitrile
• CAS NO: 24490-79-7
• Molecular Formula: C₈H₆N₂
• Molecular Weight: 130.149
• Product Categories: PYRIDINE
• Mol File: 24490-79-7.mol

Chemical Properties

• Melting Point: 70-71 °C(Solv: hexane (110-54-3))
• Boiling Point: 151-152 °C(Press: 10.5 Torr)
• Appearance: /
• Density: 1.112±0.06 g/cm3(Predicted)
• PKA: 4.40±0.26(Predicted)
• CAS DataBase Reference: 2-Propenenitrile,3-(4-pyridinyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenenitrile,3-(4-pyridinyl)-(9CI)(24490-79-7)
• EPA Substance Registry System: 2-Propenenitrile,3-(4-pyridinyl)-(9CI)(24490-79-7)

Safety Data

• Hazardous Substances Data: 24490-79-7(Hazardous Substances Data)

Usage

Properties

Unsaturated nitrile
Flammable liquid
High vapor pressure
Acute toxicity risk

Uses

Organic synthesis
Building block for pharmaceuticals and agrochemicals
Intermediate in polymer and industrial chemical production

Safety Precautions

Handle and store with care
Well-ventilated area
Wear appropriate personal protective equipment

Upstream product

• 103028-58-6 (E)-2-cyano-3-(pyridin-4-yl)acrylic acid 
• 872-85-5 pyridine-4-carbaldehyde 
• 1121-60-4 pyridine-2-carbaldehyde 

Downstream Products

• 622369-83-9 3-(1-methylpiperidin-4-yl)propan-1-amine 
• 501379-51-7 3-(1-oxide-4-pyridyl)propionitrile 
• 84200-06-6 3-(pyridin-4-yl)propanenitrile 
• 329971-85-9 2-phenyl-7-pyridin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine 
• 84228-93-3 3-(pyridin-4-yl)acrylic acid 

Relevant articles and documents

2-[3-(1-METHYL-PIPERIDIN-4-YL)-PROPYLAMINO]-PYRIMIDINE-5-CARBOXYLIC ACIDS AND AMIDES AND METHODS OF MAKING THE SAME

The present invention relates to certain intermediates useful in the preparation of certain benzoimidazol-2-yl pyrimidines and processes for preparing them. In particular, the present invention relates to various 2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5- carboxylic acids and amides as useful intermediates in the preparation of compounds including [5 -(4,6-Dimethyl-1 H-benzoimidazol-2-yl)-4-methyl-pyrimidin-2-yl]-[3-(1 -methyl-piperidin-4-yl)-propyl]-amine.

1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF

This invention provides a compound represented by the formula (I) :wherein R1 is a hydrogen atom, a halogen atom, hydroxy, nitro, optionally halogenated alkyl, alkoxy optionally having substituents, acyl or amino optionally having substituents;R2 is pyridyl, furyl, thienyl, pyrrolyl, quinolyl, pyrazinyl, pyrimidinyl, pyridazinyl, indolyl, tetrahydroquinolyl or thiazolyl, each of which may have substituents;n is 1 or 2; or a salt. And this invention provides a safe pharmaceutical comprising the compound of the formula (I) , which has an excellent apoptosis inhibitory effect and MIF binding effect, for preventing and/or treating heart disease, nervous degenerative disease, cerebrovascular disease, central nervous infectious disease, traumatorathy, demyelinating disease, bone and articular disease, kidney disease, liver disease, osteomyelodysplasia, AIDS, cancer, and the like.