245040-42-0Relevant articles and documents
Design and synthesis of constrained epothilone analogs: The efficient synthesis of eleven-membered rings by olefin metathesis
Winkler, Jeffrey D.,Holland, Joanne M.,Kasparec, Jiri,Axelsen, Paul H.
, p. 8199 - 8214 (2007/10/03)
The efficient synthesis of both left- and right-hand halves of a constrained analog of the anticancer natural product epothilone is described. The eleven-membered rings common to both compounds are prepared by olefin metathesis.