245040-57-7

Basic information

• Product Name: (4R,5S,6S)-2-[(4S,5R)-5-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-non-8-en-3-one
• Synonyms: (4R,5S,6S)-2-[(4S,5R)-5-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-non-8-en-3-one
• CAS NO: 245040-57-7
• Molecular Weight: 430.585
• Mol File: 245040-57-7.mol

Chemical Properties

• CAS DataBase Reference: (4R,5S,6S)-2-[(4S,5R)-5-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-non-8-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S,6S)-2-[(4S,5R)-5-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-non-8-en-3-one(245040-57-7)
• EPA Substance Registry System: (4R,5S,6S)-2-[(4S,5R)-5-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-non-8-en-3-one(245040-57-7)

Safety Data

• Hazardous Substances Data: 245040-57-7(Hazardous Substances Data)

Upstream product

• 61866-32-8 (S)-2-methyl-4-pentenal 
• 245040-42-0 2-[(4S,5R)-5-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-2-methyl-pentan-3-one 
• 245040-40-8 (2S,3S)-2-Allyl-3-hydroxy-4,4-dimethyl-1-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-heptane-1,5-dione 
• 245040-41-9 (2R,3S)-2-Allyl-4,4-dimethyl-heptane-1,3,5-triol 
• 106921-60-2 2,2-dimethyl-3-oxopentanal 
• 128461-58-5 (4S,5R)-4-Methyl-3-(pent-4-enoyl)-5-phenyl-1,3-oxazolidin-2-one 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 

Downstream Products

• 245040-43-1 (4R,5S,6S)-2-[(4S,5R)-5-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-5-(tert-butyl-dimethyl-silanyloxy)-2,4,6-trimethyl-non-8-en-3-one 

Relevant articles and documents

Design and synthesis of constrained epothilone analogs: The efficient synthesis of eleven-membered rings by olefin metathesis

The efficient synthesis of both left- and right-hand halves of a constrained analog of the anticancer natural product epothilone is described. The eleven-membered rings common to both compounds are prepared by olefin metathesis.