245729-77-5

Upstream product

• 3780-28-7 3-(5-methyl-1H-pyrrole-2-carboxylate) of 6-deoxy-5-C-methyl-4-O-methyl-L-lyxo-hexopyranose 
• 229307-67-9 4-(diphenylmethoxy)-7-hydroxy-8-methyl-2H-1-benzopyran-2-one 
• 229308-91-2 4-benzhydryloxy-8-methyl-7-(tetrahydro-pyran-2-yloxy)-chromen-2-one 
• 200726-75-6 3-(5-methyl-1-H-pyrrole-2-carboxylate) of phenylmethyl-6-deoxy-5-C-methyl-4-O-methyl-L-lyxo-hexopyranoside 
• 200726-79-0 4-hydroxy-8-methyl-7-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-1-benzopyran-2-one 
• 200726-78-9 1-[2-hydroxy-3-methyl-4-[(tetrahydro-2H-pyran-2-yl)oxy]]phenyl ethanone 
• 200726-73-4 phenylmethyl-2,3-O-carbonyl-6-deoxy-5-C-methyl-4-O-methyl-L-lyxo-hexopyranoside 
• 200726-70-1 phenylmethyl-6-deoxy-5-C-methyl-4-O-methyl-L-lyxo-hexopyranoside 
• 245729-75-3 (R)-1-((4S,5S)-5-Hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methoxy-2-methyl-propan-2-ol 
• 101967-82-2 4-O-methyl-5,5-di-C-methyl-2,3-O-(1-methylethylidene)-L-lyxopyranose 
• 10139-84-1 1-(2,4-dihydroxy-3-methylphenyl)ethanone 
• 264891-36-3 L-lyxo-O²,O³-isopropylidene-5,O⁴-dimethyl-6-deoxy-hexonic acid-lactone 
• 107739-83-3 (+)-6-deoxy-5-C,4-O-dimethyl-L-xylo-hexopyranose 
• 374749-51-6 5-Methyl-1H-pyrrole-2-carboxylic acid (3aR,6R,7R,7aR)-6-methoxy-2,2,5,5-tetramethyl-tetrahydro-[1,3]dioxolo[4,5-b]pyran-7-yl ester 

Downstream Products

• 245729-78-6 5-methyl-1H-pyrrole-2-carboxylic acid 6-(4-benzhydryloxy-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-5-(tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester 
• 4434-05-3 coumermycin A1 

Relevant academic research and scientific papers

Synthesis of coumermycin A1

A concise synthesis of the antibiotic coumermycin A1, a natural product isolated from streptomyces, was achieved. In a key step, a selectively protected noviose sugar was prepared from novobiocin through a transglycosylation reaction with aceto

Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B

The design, synthesis, and in vitro biological activity of a series of novel coumarin inhibitors of gyrase B is presented. Replacement of the 3- acylamino residue (3-NHCOR) of coumarin drags with reversed isosteres C(=O)R, C(=N-OR)R', COOR, CONHR and CONH