2458-53-9

Basic information

• Product Name: (22E,24R)-24-Methylcholesta-5,22-dien-3β-ol acetate
• Synonyms: (22E,24R)-24-Methylcholesta-5,22-dien-3β-ol acetate;Acetic acid (22E)-ergosta-5,22-dien-3β-yl ester
• CAS NO: 2458-53-9
• Molecular Formula: C₃₀H₄₈O₂
• Molecular Weight: 440.70092
• Mol File: 2458-53-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 157-158 °C
• Boiling Point: 501.2±29.0 °C(Predicted)
• Appearance: /
• Density: 1.00±0.1 g/cm3(Predicted)
• CAS DataBase Reference: (22E,24R)-24-Methylcholesta-5,22-dien-3β-ol acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (22E,24R)-24-Methylcholesta-5,22-dien-3β-ol acetate(2458-53-9)
• EPA Substance Registry System: (22E,24R)-24-Methylcholesta-5,22-dien-3β-ol acetate(2458-53-9)

Safety Data

• Hazardous Substances Data: 2458-53-9(Hazardous Substances Data)

Upstream product

• 64-19-7 acetic acid 
• 28421-56-9 3β-acetoxy-5α,8α-(4-phenyl-1,2,4-triazolidine-3,5-dione-1,2-diyl)ergosta-6,22-diene 
• 474-67-9 Brassicasterol 
• 474-67-9 BRASSICASTEROL 
• 108-24-7 acetic anhydride 

Downstream Products

• 474-67-9 BRASSICASTEROL 
• 92032-32-1 (-)(R)-Methyl-isopropyl-acetaldehyd-benzoylhydrazon 
• 1474-14-2 3β-acetoxybisnor-5-cholenic acid 
• 14287-61-7 (2R)-2,3-Dimethylbutanoic acid 

Relevant articles and documents

Marine Natural Products: Part I - Occurence of Batyl Alcohol and Brassicasterol in Porites lutea

Batyl alcolhol (octadecylglycerol) and brassicasterol (-24-methylcholesta-5,22E-dien-3β-ol) have been isolated from Porites lutea, a stony coral from the west coast of India.

Sterochemical Aspects of Acid-Catalyzed Cyclopropane Ring-Opening Reactions. A Stereospecific Pathway to Crinosterol and Brassicasterol

It is shown that the acid-catalyzed ring-opening of the two diastereoisomeric 23,24-methylenecholosterols 3 and 5 on treatment with gaseous HCl in acetic acid leads sterospecifically to the naturally occuring crinosterol (4) and brassicasterol (6), respectively (Scheme 1).This isomerization can be viewed as a biomimetic model of an in vivo methylation process of the type already known in plant sterol metabolism (cf. cycloeucalenol --> obtusifoliol, 1-->2).The synthetic application of this method provides a convenient labelling of sterol side chain for tracer experiments.The mechanistic features of the reaction with respect to its particular stereospecificity are discussed.