246022-83-3Relevant academic research and scientific papers
NEW COMPOUNDS SUITABLE AS CATALYSTS FOR POLYMERIZATION REACTIONS
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Page/Page column 54; 57-58, (2019/04/10)
The invention relates to a compound of formula (I) and a process for synthesizing said compound. The invention further relates to the use of said compound as a catalyst, preferably for polymerization, such as, olefin polymerization. The invention also relates to the polymers produced using said catalyst and articles comprising said polymers.
Thiosemicarbazones derived from 1-indanones as new anti-Trypanosoma cruzi agents
Caputto, María E.,Fabian, Lucas E.,Benítez, Diego,Merlino, Alicia,Ríos, Natalia,Cerecetto, Hugo,Moltrasio, Graciela Y.,Moglioni, Albertina G.,González, Mercedes,Finkielsztein, Liliana M.
experimental part, p. 6818 - 6826 (2011/12/22)
In the present work, we synthesized a series of thiosemicarbazones derived from 1-indanones with good anti-Trypanosoma cruzi activity. Most of them displayed remarkable trypanosomicidal activity. All the compounds showed nonspecific cytotoxicity on human erythrocytes. The ability of the new compounds to inhibit cruzipain, the major cysteine protease of T. cruzi, was also explored. Thiosemicarbazones 12 and 24 inhibited this enzyme at the dose assayed. This interaction was also studied in terms of molecular docking.
Synthetic studies of the formation of pyrazoloisoquinolines
Bryan Miller,Stowell, Joseph G,Dugar, Sundeep,Moock, Thomas E,Jenks, Christopher W,Farmer, Steven C,Phan, Bach,Wujcik, Chad E,Olmstead, Marilyn M
, p. 6061 - 6067 (2007/10/03)
Diazotization of 7-amino-5,8-dimethyl-6-(phenylthio)isoquinoline unexpectedly led to the formation of a new ring system, 3H-pyrazolo[3,4-h]isoquinoline as its 5-methyl-6-phenylthio derivative. In this work, the parent ring system was synthesized and chara
