24624-78-0

Usage

Uses

Used in Organic Synthesis:
(4-NITRO)PHENYL-2,3,4-TRI-O-ACETYL-BETA-D-XYLOPYRANOSIDE is used as an intermediate in the synthesis of p-Nitrophenyl β-D-Xylopyranoside (N509050) for its role in organic synthesis. The compound serves as a key building block in the preparation of various complex organic molecules, particularly those involving the xylopyranoside moiety. Its unique structural features make it a valuable component in the development of novel chemical entities with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4-NITRO)PHENYL-2,3,4-TRI-O-ACETYL-BETA-D-XYLOPYRANOSIDE is used as a precursor for the development of new drugs. Its structural properties allow for the creation of molecules with specific biological activities, which can be tailored to target various diseases and conditions. The compound's versatility in organic synthesis makes it a promising candidate for the development of innovative therapeutic agents.
Used in Research and Development:
(4-NITRO)PHENYL-2,3,4-TRI-O-ACETYL-BETA-D-XYLOPYRANOSIDE is also utilized in research and development for the study of various chemical reactions and mechanisms. Its unique structure provides researchers with valuable insights into the reactivity and behavior of similar compounds, contributing to the advancement of knowledge in the field of organic chemistry.

Upstream product

• 100-02-7 4-nitro-phenol 
• 3068-31-3 1-bromo-2,3,4-tri-O-acetyl-α-D-xylopyranose 
• 3945-26-4 α-D-xylopyranosyl fluoride 
• 108-24-7 acetic anhydride 
• 2001-96-9 p-nitrophenyl β-D-xylopyranoside 
• 87-72-9 D-Xylose 
• 4049-33-6 tetra-O-acetyl-β-D-xylopyranose 
• 3068-31-3 2,3,4-tri-O-acetyl-α-D-xylopyranosyl bromide 
• 62446-93-9 1,2,3,4-tetra-O-acetyl-D-xylopyranose 

Downstream Products

• 2001-96-9 p-nitrophenyl β-D-xylopyranoside 
• 17453-88-2 p-Acetamidophenyl-tri-O-acetyl-β-D-xylopyranosid 
• 144683-70-5 p-nitrophenyl O-β-D-galactopyranosyl-(1->4)-β-D-xylopyranoside 
• 144683-69-2 p-nitrophenyl O-β-D-galactopyranosyl-(1->3)-β-D-xylopyranoside 
• 17306-77-3 4-aminophenyl 2,3,4-tri-O-acetyl-β-D-xylopyranoside 
• 173468-31-0 4-nitrophenyl O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-bis4)>-2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-25-2 4-nitrophenyl O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-O-(2,3-di-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-14-9 4-nitrophenyl O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-35-4 4-nitrophenyl O-β-D-xylopyranosyl-(1<*>4)-bis4)>-β-D-xylopyranoside 
• 173468-11-6 4-nitrophenyl 2,3-di-O-benzoyl-4-O-chloroacetyl-β-D-xylopyranoside 
• 173468-29-6 4-nitrophenyl O-β-D-xylopyranosyl-(1<*>4)-O-β-D-xylopyranosyl-(1<*>4)-β-D-xylopyranoside 
• 173468-12-7 4-nitrophenyl 2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-09-2 4-nitrophenyl 4-O-chloroacetyl-β-D-xylopyranoside 
• 6819-07-4 p-nitrophenyl β-D-xylopyranosyl-(1->4)-β-D-xylopyranoside 

Relevant academic research and scientific papers

Propargyl-containing xylose and synthesis method thereof

The invention discloses propargyl-containing xylose and a preparation method thereof. The method comprises the following steps: using D-xylose as a raw material, carrying out full acetyl protection onthe D-xylose, introducing p-nitrophenoxy into a first position of an obtained compound, and removing acetyl to obtain a compound A; introducing tert-butyl dimethyl into the position 2, the position 3or the position 4 of the obtained compound A to obtain a compound B, a compound C and a compound D, and separating the compound B, the compound C and the compound D; and respectively carrying out acetyl protection on hydroxyl groups of the compound B, the compound C and the compound D, then removing the tert-butyl dimethyl, and respectively introducing propargyl into the position 2, the position3 and the position 4 to obtain the propargyl-containing xylose. According to the method disclosed by the invention, the propargyl is selectively connected to xylose for the first time by using a method for carrying out occupying by using tert-butyl dimethyl (TBS), so that a platform is provided for subsequent connection of the xylose to protein or amino acid, and a foundation is laid for biological research in the future.

The application of aryl substituted derivatives of xylose as environmentally friendly multipurpose pesticides

A series of aryl substituted derivatives of xylose have been synthesized. Biological tests have revealed high fungicidal activity of the resulting compounds against various phythopathogenic fungi. Additional biological studies have demonstrated high plant growth regulatory activity of the compounds synthesized.

Synthesis and inhibitory activity evaluation of 2,6-disubstituted purine derivatives

A series of novel 2,6-disubstituted purine derivatives were designed and synthesized from 2,6-dichloropurine. The structures of target compounds were determined by 1H-NMR, 13C-NMR, and HRMS. The synthesized compounds were evaluated for their inhibitory activities against lung cancer cell lines of A549 and liver cancer cell lines of Bel-7402. 2-(4-Benzyloxy-phenylamino)-6-(cyclohexylamino)purine(3), 2-(4-chloro-phenylamino)-6-(n-butylamino)purine (5), 2-(4-morpholinoamino)-6-(4-hydroxy-phenylamino)purine (9), and 2-(4-O-galactosyl-phenylamino)-6-(cyclohexylamino)purine (12) exhibited moderate inhibitory activity.

Glycosynthase with broad substrate specificity-an efficient biocatalyst for the construction of oligosaccharide library

A versatile glycosynthase (TnG-E338A) with strikingly broad substrate scope has been developed from Thermus nonproteolyticus β-glycosidase (TnG) by using site-directed mutagenesis. The practical utility of this biocatalyst has been demonstrated by the facile generation of a small library containing various oligosaccharides and a steroidal glycoside (total 25 compounds) in up to 100 % isolated yield. Moreover, an array of eight gluco-oligosaccharides has been readily synthesized by the enzyme in a one-pot, parallel reaction, which highlights its potential in the combinatorial construction of a carbohydrate library that will assist glycomic and glycotherapeutic research. Significantly, the enzyme provides a means by which glycosynthase technology may be extended to combinatorial chemistry.

Glycosynthase-Mediated Assembly of Xylanase Substrates and Inhibitors

An exo-β-xylosidase mutant with glycosynthase activity was created to aid in the synthesis of xylanase substrates and inhibitors. Simple monosaccharides were easily elaborated into di-, tri- and tetrasaccharides by using this enzyme. Some products proved

Synthesis of 2- and 4-nitrophenyl β-glycosides of β-(1 → 4)-D-xylo-oligosaccharides of dp 2-4

2- and 4-Nitrophenyl β-D-xylopyranosides (4 and 5) were transformed, via dibutyltin oxide-mediated acylation, into the corresponding 2,3-di-O-benzoyl derivatives 11 and 15. Xylobiose and xylotriose were easily isolated by charcoal column chromatography from a commercially available material and converted into the di- and trisaccharide methyl 1-thio-β-glycosides 36 and 37. The 2- and 4-nitrophenyl β-glycosides of the β-(1 → 4)-D-xylo-oligosaccharides of dp 2-4 were synthesized by N-iodosuccinimide-silver triflate-promoted condensation using 11 and 15 as the glycosyl acceptors and ethyl 1-thio-β-D-xylopyranoside triacetate 16, 36, and 37 as the glycosyl donors. Also described are an improved preparation of 4 and 5, and the synthesis of 1-naphthyl β-D-xylopyranoside, as well as an alternative approach to the 2- and 4-nitrophenyl β-xylobiosides.