24658-23-9Relevant academic research and scientific papers
Visible-light-promoted cross-coupling reactions of aryldiazonium salts with S-methyl-D3 sulfonothioate or Se-methyl-D3 selenium sulfonate: Synthesis of trideuteromethylated sulfides, sulfoxides, and selenides
Wang, Shun-Yi,Huang, Cheng-Mi,Li, Jian,Ai, Jing-Jing,Liu, Xin-Yu,Rao, Weidong
, p. 9128 - 9132 (2020)
A novel visible-light-photocatalytic deuterated thiomethylation/methylselenation of aryldiazonium salts utilizing S/ Se-methyl-d3 sulfonothioate has been developed. The mild conditions and the various functional groups provide a green protocol for the efficient and rapid introduction of the S-CD3 or Se-CD3 group with useful levels of deuterium content (>91% D). Trideuteromethyl sulfoxides have also been successfully chemoselectively observed by simple atmospheric changes under photocatalytic conditions.
Investigation of the scope and mechanism of copper catalyzed regioselective methylthiolation of aryl halides Dedicated to Professor Dr. Irina Beletskaya
Joseph, P.J. Amal,Priyadarshini,Kantam, M. Lakshmi,Sreedhar
, p. 8276 - 8283 (2013/09/02)
Methylthiolation of structurally diverse aryl halides was accomplished under fluoride free conditions using catalytic amounts of CuI, and DMSO as the methylthiolation source. Optimization studies unveiled several varieties of promoters among which Zn(OAc)2 was found ideal. The analogous reaction with DMSO-d6 afforded corresponding deuterated aryl methyl thioether with 99% purity. Mechanistic studies revealed CuSMe as the active methylthiolation agent.
Copper-mediated methylthiolation of aryl halides with DMSO
Luo, Fang,Pan, Changduo,Li, Liping,Chen, Fan,Cheng, Jiang
scheme or table, p. 5304 - 5306 (2011/06/21)
A copper-mediated methylthiolation of aryl halides with the widely available DMSO is described. The procedure tolerates a series of functional groups such as methoxy, nitro, chloro, fluoro, trifluoromethyl, formyl and methoxycarbonyl groups. Thus, it represents a simple and facile methylthiolation procedure.
