24672-87-5Relevant academic research and scientific papers
Intramolecular cycloadditions with isobenzofurans - X. A novel synthesis of annulated hydroquinolines
Peters, Olaf,Friedrichsen, Willy
, p. 8581 - 8582 (1995)
The intramolecular Diels-Alder reaction of 1-amino substituted isobenzofuran 3 leads to hydrobenzo[h] quinolines (5,6).
Synthesis of Isoindoles from Intramolecular Condensation of Benzyl Azides with α-Aryldiazoesters
Zhu, Jing,Li, Rui,Su, Yan,Gu, Peiming
, p. 5813 - 5820 (2019/04/16)
Rh-catalyzed intramolecular condensation of the benzyl azides with α-aryldiazoesters was explored. The reaction proceeded through the nucleophilic attack of the organic azide onto a rhodium carbenoid, while releasing nitrogen gas, affording the α-imino es
Intramolecular cycloadditions with 1-aminoisobenzofurans: a simple entry into the field of polycyclic aza-compounds
Peters, Olaf,Debaerdemaeker, Tony,Friedrichsen, Willy
, p. 59 - 70 (2007/10/03)
Starting with 6-methoxyisochromane-1,3-dione (1) isobenzofuran 5 was generated in situ using the Hamaguchi-Ibata methodology. Intramolecular cycloaddition with subsequent transformations provides benzoquinolines of type 7, 8 and 9. In a similar manner 11-azasteroid analogues (22-26) were obtained, starting with 1 and amine 18. Density functional theoretical (DFT) studies of various inter- and intramolecular Diels-Alder reactions are reported.
INTRAMOLECULAR CYCLOADDITIONS WITH ISOBENZOFURANS I
Friedrichsen, Willy,Koenig, B. Michael,Hildebandt, Knut,Debaerdemaeker, Tony
, p. 297 - 302 (2007/10/02)
Intramolecular Diels-Alder reactions with isobenzofurans (5,12) offer an attractive route for the preparation of polycyclic systems (6,13).
