24677-02-9Relevant academic research and scientific papers
Preparation of tertiary amides via aryl, heteroaryl, and benzyl organozinc reagents; Scope and limitations
Rieke, Reuben D.,Kim, Seung-Hoi
experimental part, p. 3478 - 3481 (2012/08/13)
A facile synthetic protocol for the preparation of tertiary amides has been developed. The title compounds have been successfully obtained by the Pd-catalyzed cross-coupling reactions of readily available aryl and benzyl organozinc reagents with the appropriate carbamoyl chlorides.
Synthesis of tertiary benzamides via Pd-catalyzed coupling of arylboronic esters and carbamoyl chlorides
Lysen, Morten,Kelleher, Susan,Begtrup, Mikael,Kristensen, Jesper Langgaard
, p. 5342 - 5343 (2007/10/03)
Ortho-substituted arylboronic esters are efficiently coupled with carbamoyl chlorides under Pd-catalysis to give tertiary benzamides.
A ONE-POT CONVERSION OF CYCLIC ANHYDRIDES TO ETHYL ω-DIALKYLAMINOALKANOATES
Bell, Kevin H.,Fullick, Graeme
, p. 1965 - 1970 (2007/10/02)
Ethyl ω-dialkylaminoalkanoates are conveniently obtained in good yield by a one-pot procedure from cyclic anhydrides by successive treatment with a secondary amine, triethyloxonium fluoroborate, and sodium borohydride.
