246853-44-1

Basic information

• Product Name: 2,2'-dimethylbenzhydrylamine
• Synonyms: 2,2'-dimethylbenzhydrylamine
• CAS NO: 246853-44-1
• Molecular Weight: 211.307
• Mol File: 246853-44-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,2'-dimethylbenzhydrylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-dimethylbenzhydrylamine(246853-44-1)
• EPA Substance Registry System: 2,2'-dimethylbenzhydrylamine(246853-44-1)

Safety Data

• Hazardous Substances Data: 246853-44-1(Hazardous Substances Data)

Upstream product

• 22627-01-6 bis(2-methylphenyl)methanimine 
• 108714-78-9 bis-o-tolyl N-hydroxyoxime 
• 95-46-5 2-methylphenyl bromide 
• 2845-91-2 bis(2-methylphenyl)methanol 
• 529-20-4 2-methylphenyl aldehyde 
• 932-31-0 ortho-tolylmagnesium bromide 
• 529-19-1 2-Methylbenzonitrile 

Downstream Products

• 246853-45-2 bis-o-tolylmethylamine bromoacetamide 
• 1072879-59-4 N-benzylidene-bis(2-methylphenyl)methylamine 
• 1423035-73-7 (S)-N¹-[di(o-tolyl)methyl]-N²-(1-hydroxy-3,3-dimethylbutan-2-yl)oxalamide 
• 1423035-67-9 ethyl 2-{[di(o-tolyl)methyl]amino}-2-oxoacetate 

Relevant articles and documents

Pd-catalyzed enantioselective C-H iodination: Asymmetric synthesis of chiral diarylmethylamines

An enantioselective C-H iodination reaction using a mono-N-benzoyl- protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.

Design of Bronsted acid-assisted chiral Bronsted acid catalyst bearing a bis(triflyl)methyl group for a Mannich-type reaction

A new Bronsted acid-assisted chiral Bronsted (chiral BBA) acid catalyst (1) was developed by substituting a hydroxy group of optically active 1,1′-bi(2-naphthol) with a stronger Bronsted acidic group such as a bis(trifluoromethanesulfonyl)methyl group. The enantioselective Mannich-type reaction of ketene silyl acetals with aldimines catalyzed by (R)-1 in the presence of stoichiometric achiral proton sources gave (S)-β-amino esters in high yield with moderate to good enantiomeric excesses.