247025-16-7

Basic information

• Product Name: 3'-azido-5'-O-tert-butyldiphenylsilyl-3'-deoxy-2'-O,4'-C-methylene-5-methyluridine
• Synonyms: 3'-azido-5'-O-tert-butyldiphenylsilyl-3'-deoxy-2'-O,4'-C-methylene-5-methyluridine
• CAS NO: 247025-16-7
• Molecular Weight: 533.659
• Mol File: 247025-16-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3'-azido-5'-O-tert-butyldiphenylsilyl-3'-deoxy-2'-O,4'-C-methylene-5-methyluridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-azido-5'-O-tert-butyldiphenylsilyl-3'-deoxy-2'-O,4'-C-methylene-5-methyluridine(247025-16-7)
• EPA Substance Registry System: 3'-azido-5'-O-tert-butyldiphenylsilyl-3'-deoxy-2'-O,4'-C-methylene-5-methyluridine(247025-16-7)

Safety Data

• Hazardous Substances Data: 247025-16-7(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 153914-98-8 3-Azido-5-O-benzoyl-4-C-benzoyloxymethyl-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 
• 247025-10-1 3-Azido-3-deoxy-4-C-hydroxymethyl-1,2-O-isopropylidene-α-D-erythro-pentofuranose 
• 247025-11-2 3'-azido-5'-O-tert-butyldiphenylsilyl-3'-deoxy-4'-hydroxymethyl-1',2'-O-isopropylidene-α-D-ribofuranose 

Relevant articles and documents

Synthesis of a conformationally locked AZT analogue, 3'-azido-3'-deoxy- 2'-O,4'-C-methylene-5-methyluridine

A bicyclic 3'-azido-3'-deoxythymidine (AZT) analogue with a locked N- conformation, 3'-azido-3'-deoxy-2'-O,4'-C-methylene-5-methyluridine (1a), and its 3'-amino derivative, 3'-amino-3'-deoxy-2'-O,4'-C-methylene-5- methyluridine (1b), were successfully synthesized from D-glucose. The conformation of 1a was also discussed by means of 1H NMR measurements and a molecular modeling (PM3) study.