247127-60-2

Basic information

• Product Name: methyl 4-(2-tert-butoxycarbonylamino-ethoxy)-2-hydroxy-benzoate
• Synonyms: methyl 4-(2-tert-butoxycarbonylamino-ethoxy)-2-hydroxy-benzoate
• CAS NO: 247127-60-2
• Molecular Weight: 311.335
• Mol File: 247127-60-2.mol

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-tert-butoxycarbonylamino-ethoxy)-2-hydroxy-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-tert-butoxycarbonylamino-ethoxy)-2-hydroxy-benzoate(247127-60-2)
• EPA Substance Registry System: methyl 4-(2-tert-butoxycarbonylamino-ethoxy)-2-hydroxy-benzoate(247127-60-2)

Safety Data

• Hazardous Substances Data: 247127-60-2(Hazardous Substances Data)

Upstream product

• 2150-47-2 methyl 2,4-dihydroxybenzoate 
• 26690-80-2 2-(N-tert-butoxycarbonylamino)ethanol 

Downstream Products

• 959838-37-0 tert-butyl 2-(3-benzyloxy-4-(4-(1-methyl-1H-indol-5-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-phenoxy)-ethylcarbamate 
• 959838-36-9 tert-butyl 2-(3-benzyloxy-4-formyl-phenoxy)-ethylcarbamate 

Relevant articles and documents

Parallel solid-phase synthesis of vitronectin receptor (αvβ3) inhibitors

A combinatorial approach for rapid optimization of a vitronectin receptor (αvβ3) inhibitor lead was accomplished by solid-phase synthesis. Orthogonally bis protected 2,3-diaminopropionic acid was used to immobilize the C-terminus of the molecule. Selective deprotection and functionalization of the α-amino group followed by acyl resorcinol scaffold attachment and N-terminus diversification was used to explore structure-activity relationship (SAR). (C) 2000 Elsevier Science Ltd. All rights reserved.

TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.