247142-68-3Relevant articles and documents
Synthesis of 6-membered cyclic carbonates from 1,3-diols and low CO2 pressure: A novel mild strategy to replace phosgene reagents
Gregory, Georgina L.,Ulmann, Marion,Buchard, Antoine
, p. 39404 - 39408 (2015)
Low pressure carbon dioxide is used as the carbonation agent in a simple, safe and efficient procedure for the synthesis of 6-membered cyclic carbonates from 1,3-diols. Using readily available reagents and proceeding at room temperature, this route offers a novel mild alternative to phosgene derivatives.
Immuno-polymeric nanoparticles by Diels-Alder chemistry
Shi, Meng,Wosnick, Jordan H.,Ho, Karyn,Keating, Armand,Shoichet, Molly S.
, p. 6126 - 6131 (2007)
(Figure Presented) Hitting the target: Self-assembled polymeric nanoparticles from an amphiphilic copolymer were prepared with furan groups on the outer polyethylene glycol corona that were accessible for Diels-Alder reactions with maleimide-functionalize
Degradation behavior of poly(lactide-co-carbonate)s controlled by chain sequences
Liu, Xinli,Cui, Dongmei,Hua, Xiufang
, p. 5289 - 5296 (2020/09/02)
Immortal copolymerization of lactide (LA) and 2-methyl-2-benzyloxycarbonyl-1,3-trimethylene carbonate (MBC) affords random, tapered, and diblock microstructured poly(lactide-co-carbonate)s. Subsequent debenzylation of these poly(LA-co- MBC)s by Pd/C catalytic hydrogenation gives poly(LA-co-MCC)s containing carboxylic acid, which show controlled degradation performance during in vitro hydrolytic degradation experiments. The degradation rates of poly(LA-co-MCC)s are proved for the first time to be affected significantly by lactide-carbonate linkages in the main chains, following the trend of lactide-carbonate unit (L- C/C-L)>carbonate-carbonate unit (C-C)>lactide-lactide unit (L-L). The resultant hydrolysis products are the precursors for synthesizing the corresponding monomers. Therefore, the degradable and recyclable materials are accomplished.
Highly Stable, Coordinated Polymeric Nanoparticles Loading Copper(II) Diethyldithiocarbamate for Combinational Chemo/Chemodynamic Therapy of Cancer
Peng, Xinyu,Pan, Qingqing,Zhang, Boya,Wan, Shiyu,Li, Sai,Luo, Kui,Pu, Yuji,He, Bin
, (2019/06/17)
Disulfiram (DSF) has excellent in vitro anticancer activity in the presence of Cu(II). The anticancer mechanism studies have demonstrated that copper(II) diethyldithiocarbamate, Cu(DDC)2, is the crucial DSF's metabolite exhibiting anticancer ac
