24716-96-9

Basic information

• Product Name: trans 2-(aminomethyl)cyclohexylamine
• CAS NO: 24716-96-9
• Molecular Weight: 128.217
• Mol File: 24716-96-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: trans 2-(aminomethyl)cyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: trans 2-(aminomethyl)cyclohexylamine(24716-96-9)
• EPA Substance Registry System: trans 2-(aminomethyl)cyclohexylamine(24716-96-9)

Safety Data

• Hazardous Substances Data: 24716-96-9(Hazardous Substances Data)

Upstream product

• 1469-49-4 6-carbamoylcyclohex-3-enecarboxylic acid 
• 1436-60-8 ethyl cis-2-amino-1-cyclohexanecarboxylate 
• 6294-84-4 cis-1-carboxy-2-(aminocarboxyl)-2-cyclohexane 
• 24717-02-0 cis-2-aminocyclohexanecarbohydrazide 
• 24716-89-0 trans 2-(aminomethyl)cyclohexylamine 

Downstream Products

• 26685-87-0 (1R,2S)-1-amino-2-aminomethylcyclohexane 
• 26853-51-0 (1S,2S)-1-amino-2-aminomethylcyclohexane 
• 26853-49-6 (1R,2R)-1-amino-2-aminomethylcyclohexane 
• 118488-71-4 <2-(13)C>-cis-decahydroquinazoline 
• 24716-87-8 cis-decahydroquinazoline 

Relevant articles and documents

An effective approach to the enantiomers of alicyclic β-aminonitriles by using lipase catalysis

Lipase-catalyzed N-acylations of racemic cis- and trans-2- aminocyclopentane- (and cyclohexane-) carbonitriles with 2,2,2-trifluoethyl butanoate in tert-butyl methyl ether (TBME) and in room-temperature ionic liquids (RTILs) were studied. The racemates were effectively resolved (E >200) on a preparative scale by lipase PS-C II (lipase from Burkholderia cepacia) in TBME, resulting in two enantiomers in their enantiopure forms at 50% conversion. The reactions in RTILs with Novozym 435 (Candida antarctica lipase B) were slow and proceeded with low enantioselectivity.

Platinum complex

New platinum complex represented by the general formula [I]: STR1 wherein R1 and R2 are same and represent halogen atom or NO3, or R1 is SO4 and R2 is H2 O, or R1 and R2 are bonded with each other to form either STR2 and the configuration of 1-aminomethyl-2-aminocyclohexane is selected from trans-1, trans-d, cis-1 and cis-d. The compounds of the formula [I] are active against tumor and are expected to be useful as medicaments.