26685-87-0

Basic information

• Product Name: trans 2-(aminomethyl)cyclohexylamine
• CAS NO: 26685-87-0
• Molecular Weight: 128.217
• Mol File: 26685-87-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: trans 2-(aminomethyl)cyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: trans 2-(aminomethyl)cyclohexylamine(26685-87-0)
• EPA Substance Registry System: trans 2-(aminomethyl)cyclohexylamine(26685-87-0)

Safety Data

• Hazardous Substances Data: 26685-87-0(Hazardous Substances Data)

Upstream product

• 24717-02-0 cis-2-aminocyclohexanecarbohydrazide 
• 6294-84-4 cis-1-carboxy-2-(aminocarboxyl)-2-cyclohexane 
• 1436-60-8 ethyl cis-2-amino-1-cyclohexanecarboxylate 
• 1469-49-4 6-carbamoylcyclohex-3-enecarboxylic acid 
• 24716-89-0 trans 2-(aminomethyl)cyclohexylamine 

Downstream Products

• 24716-96-9 (1S,2R)-trans-(+)-1-amino-2-aminomethylcyclohexane 
• 26853-51-0 (1S,2S)-1-amino-2-aminomethylcyclohexane 
• 26853-49-6 (1R,2R)-1-amino-2-aminomethylcyclohexane 
• 118488-71-4 <2-(13)C>-cis-decahydroquinazoline 
• 24716-87-8 cis-decahydroquinazoline 

Relevant articles and documents

An effective approach to the enantiomers of alicyclic β-aminonitriles by using lipase catalysis

Lipase-catalyzed N-acylations of racemic cis- and trans-2- aminocyclopentane- (and cyclohexane-) carbonitriles with 2,2,2-trifluoethyl butanoate in tert-butyl methyl ether (TBME) and in room-temperature ionic liquids (RTILs) were studied. The racemates were effectively resolved (E >200) on a preparative scale by lipase PS-C II (lipase from Burkholderia cepacia) in TBME, resulting in two enantiomers in their enantiopure forms at 50% conversion. The reactions in RTILs with Novozym 435 (Candida antarctica lipase B) were slow and proceeded with low enantioselectivity.

Nuclear Magnetic Resonance and Circular Dichroism Spectra of 2-(Aminomethyl)cyclohexylamine Platinum(II) Complexes

Six-membered platinum(II) complexes of 2-(aminomethyl)cyclohexylamine (=amcha), whose four isomers are (1R,2R)-, (1S,2S)-, (1R,2S)-, and (1S,2R)-amcha, were synthesized.The conformations of Cl2, Cl2. Cl2, and Cl2 were determined by 1H-NMR, 13C-NMR, and CD spectra.It is proposed that Cl2 and Cl2 take a fixed chair form with a dihedral angle (Pt-N-C(1)-C(6)) of 180 deg, while Cl2 and Cl2 are interconverting between two chair forms.