247167-07-3

Basic information

• Product Name: L-Phenylalanine, N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester
• CAS NO: 247167-07-3
• Molecular Formula: C19H22N2O6S
• Molecular Weight: 406.459
• Mol File: 247167-07-3.mol

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester(247167-07-3)
• EPA Substance Registry System: L-Phenylalanine, N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester(247167-07-3)

Safety Data

• Hazardous Substances Data: 247167-07-3(Hazardous Substances Data)

Upstream product

• 63-91-2 L-phenylalanine 
• 15100-75-1 L-phenylalanine tert-butyl ester hydrochloride 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 16874-17-2 L-phenylalanine tert-butyl ester 

Downstream Products

• 1151800-81-5 N-(2,3,5-tri-O-acetyl-α-L-arabinofuranos-1-yl)-N-(2-nitrobenzenesulfonyl)-L-phenylalanine t-butyl ester 
• 1151800-82-6 N-(2,3,5-tri-O-acetyl-β-L-arabinofuranos-1-yl)-N-(2-nitrobenzenesulfonyl)-L-phenylalanine t-butyl ester 
• 845777-57-3 N-(o-nitrobenzenesulfonyl)-N-methyl-L-phenylalanine tert-butyl ester 
• 757242-11-8 (S)-2-[(2-Nitro-benzenesulfonyl)-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-amino]-3-phenyl-propionic acid 
• 86334-92-1 N-(1-deoxy-D-fructos-1-yl)-L-phenylalanine 
• 370579-79-6 (S)-2-[(2-Nitro-benzenesulfonyl)-((2R,3R,4S,5R,6S)-3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-ylmethyl)-amino]-3-phenyl-propionic acid 
• 114525-94-9 tert-butyl (2S)-2-(methylamino)-3-phenylpropanoate 

Relevant articles and documents

Structure-Permeability Relationship of Semipeptidic Macrocycles - Understanding and Optimizing Passive Permeability and Efflux Ratio

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Amino-acid derived 2-nitrobenzenesulfonamides were successfully condensed under Mitsunobu conditions with 2,3,4,6-tetra-O-acetyl-D-glucose to afford the fully protected glucosylamines in excellent yield. Upon total deprotection, these compounds rearranged to provide the corresponding Amadori products in good overall yield.