24719-09-3 Usage
Uses
Used in Pharmaceutical Industry:
3-Aminopyrazino-2-hydroxamic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to inhibit histone deacetylase enzymes, which are crucial in regulating gene expression and cell growth. This application is particularly relevant in the development of treatments for diseases where these processes are dysregulated.
Used in Enzyme Inhibition:
3-Aminopyrazino-2-hydroxamic acid is used as an enzyme inhibitor for its potential to suppress the activity of histone deacetylase, which can have therapeutic benefits in conditions where the regulation of gene expression and cell growth is compromised.
Used in Antibacterial and Antifungal Agents:
3-Aminopyrazino-2-hydroxamic acid is used as an active ingredient in antibacterial and antifungal agents due to its demonstrated properties against certain types of bacteria and fungi, offering potential applications in the treatment of infections.
Used in Research and Development:
3-Aminopyrazino-2-hydroxamic acid is used as a research compound for studying its effects on biological systems, including its potential role in the development of new drugs and medical treatments, as well as understanding its mechanism of action in inhibiting specific enzymes and its antimicrobial properties.
Check Digit Verification of cas no
The CAS Registry Mumber 24719-09-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,7,1 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 24719-09:
(7*2)+(6*4)+(5*7)+(4*1)+(3*9)+(2*0)+(1*9)=113
113 % 10 = 3
So 24719-09-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N4O2/c6-4-3(5(10)9-11)7-1-2-8-4/h1-2,11H,(H2,6,8)(H,9,10)
24719-09-3Relevant academic research and scientific papers
Study on the iodine-catalyzed reaction of 3-aminopyrazine-2-carbohydrazide and 2-(arylethynyl)benzaldehydes
Pan, Wan-Chen,Liu, Jian-Quan,Wang, Xiang-Shan
, p. 1468 - 1475 (2018/02/19)
At 60 °C in DMSO, the iodine-catalyzed reaction of 3-aminopyrazine-2-carbohydrazide and 2-(arylethynyl)benzaldehydes led hydrazones. Increasing the reaction temperature to 100 °C, the amino and amido still indicated inactive, only the imine took part in the addition of acetylene bond to give 2-arylisoquinolines in high yields with the cleavage of N-N bond unexpectedly under metal-free conditions.
