24719-39-9Relevant academic research and scientific papers
Heterocyclic cellular lipid peroxidation inhibitors inspired by the marine antioxidant barettin
Labrière, Christophe,Andersen, Jeanette H.,Albrigtsen, Marte,Hansen, J?rn H.,Svenson, Johan
, p. 106 - 114 (2019)
The marine environment remains a rich source for the discovery and development of novel bioactive compounds. The present paper describes the design, synthesis and biological evaluation of a library of small molecule heterocyclic mimetics of the marine 2,5
Chiral 1,2,3-Triazolium Salt Catalyzed Asymmetric Mono- and Dialkylation of 2,5-Diketopiperazines with the Construction of Tetrasubstituted Carbon Centers
Yang, Ju-Song,Lu, Ka,Li, Chen-Xiao,Zhao, Zu-Hang,Zhang, Xiao-Ming,Zhang, Fu-Min,Tu, Yong-Qiang
supporting information, (2022/01/22)
Novel asymmetric mono- and dialkylation reactions of α-substituted 2,5-diketopiperazines catalyzed by new chiral spirocyclic-amide-derived triazolium organocatalysts have been developed, resulting in a range of enantioenriched 2,5-diketopiperazine derivatives containing one or two tetrasubstituted carbon stereocenters. The reactions feature high yields (up to 98%), and excellent cis-diastereo- and enantioselectivities (up to >20:1 dr, >99 % ee), and they provide a new asymmetric synthetic approach to important functionalized 2,5-diketopiperazine skeletons. Furthermore, a possible reaction mechanism was proposed based on both control experiments and extensive DFT calculations.
The compound for anti-skin aging and skin wrinkle improving
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Paragraph 0059-0061, (2017/06/10)
Provided is a composition applicable to alleviate skin wrinkles by obtaining and using particular components derived from salted seafood through extraction. Preferably, the compound can be used as a cosmetic composition comprising at least one among composition 1: L-Pro-L-Tyr, composition 2: L-Pro-L-Phe, and composition 3: L-Pro-L-Val. By using natural materials derived from salted seafood, a novel material free of side effects can be easily obtained, and an effect of reducing costs of production can be obtained accordingly. Also, materials which can be applied on the exterior of the skin can be obtained. Thus, suggested is a novel way to alleviate skin wrinkles by using naturally derived materials.COPYRIGHT KIPO 2016
