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FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is a chemical compound that belongs to the family of FMOC-protected amino acids. It is characterized by the presence of a cysteine residue with a diphenylmethyl (DPM) protecting group. FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is primarily utilized in peptide synthesis and chemical biology research, where the FMOC protecting group aids in the synthesis of peptide chains by shielding the amino group. Concurrently, the DPM protecting group protects the thiol group of cysteine, preventing unwanted reactions during the synthesis process. FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is recognized for its high versatility and is extensively employed in the creation of a variety of peptides and peptide-conjugates for applications in biological and pharmacological research.

247595-29-5

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247595-29-5 Usage

Uses

Used in Pharmaceutical and Biotechnology Industry:
FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is used as a building block for the synthesis of peptides for various pharmaceutical and biotechnological applications. Its role in creating specific peptide sequences is crucial for the development of new drugs and therapeutic agents.
Used in Chemical Biology Research:
In the field of chemical biology, FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is utilized as a component in the synthesis of complex peptide-based molecules. These molecules are essential for studying biological processes and for the development of probes and tools for biological investigations.
Used in Peptide Synthesis:
FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is used as a protected amino acid in peptide synthesis. The presence of the FMOC and DPM protecting groups allows for the controlled stepwise assembly of peptide chains, facilitating the production of peptides with specific sequences and functionalities.
Used in the Production of Peptide-Conjugates:
FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is employed as a key component in the synthesis of peptide-conjugates. These conjugates combine peptides with other molecules, such as drugs, dyes, or targeting agents, to create hybrid molecules with unique properties and applications in diagnostics, therapeutics, and imaging.
Overall, FMOC-S-DIPHENYLMETHYL-L-CYSTEINE is a valuable compound in the fields of chemistry and biology, playing a significant role in the synthesis of peptides and related conjugates for a wide range of applications.

Check Digit Verification of cas no

The CAS Registry Mumber 247595-29-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,7,5,9 and 5 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 247595-29:
(8*2)+(7*4)+(6*7)+(5*5)+(4*9)+(3*5)+(2*2)+(1*9)=175
175 % 10 = 5
So 247595-29-5 is a valid CAS Registry Number.

247595-29-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Fmoc-Cys(Dpm)-OH

1.2 Other means of identification

Product number -
Other names Fmoc-Cys(Bzl)-OPfp

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:247595-29-5 SDS

247595-29-5Relevant academic research and scientific papers

Acid-labile cys-protecting groups for the Fmoc/tBu strategy: Filling the gap

Gongora-Benitez, Miriam,Mendive-Tapia, Lorena,Ramos-Tomillero, Ivan,Breman, Arjen C.,Tulla-Puche, Judit,Albericio, Fernando

, p. 5472 - 5475,4 (2012/12/12)

To address the existing gap in the current set of acid-labile Cys-protecting groups for the Fmoc/tBu strategy, diverse Fmoc-Cys(PG)-OH derivatives were prepared and incorporated into a model tripeptide to study their stability against TFA. S-Dpm proved to be compatible with the commonly used S-Trt group and was applied for the regioselecive construction of disulfide bonds.

Acid-labile cys-protecting groups for the Fmoc/tBu strategy: Filling the gap

Góngora-Benítez, Miriam,Mendive-Tapia, Lorena,Ramos-Tomillero, Iván,Breman, Arjen C.,Tulla-Puche, Judit,Albericio, Fernando

, p. 5472 - 5475 (2013/01/15)

To address the existing gap in the current set of acid-labile Cys-protecting groups for the Fmoc/tBu strategy, diverse Fmoc-Cys(PG)-OH derivatives were prepared and incorporated into a model tripeptide to study their stability against TFA. S-Dpm proved to be compatible with the commonly used S-Trt group and was applied for the regioselecive construction of disulfide bonds.

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