Bioorganic and Medicinal Chemistry Letters p. 2289 - 2290 (1999)
Update date:2022-08-03
Topics:
Vuligonda, Vidyasagar
Chandraratna, Roshantha A.S.
An efficient synthesis of a potent RAR antagonist is described starting from disubstituted β-naphthol. The functional groups on 2 and 3 positions of the β-naphthol 5 were elaborated into benzochromanone 8. The title compound was prepared by Suzuki coupling of the left and right hand pieces.
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