2476-76-8

Usage

Appearance

Yellow crystalline solid

Odor

Distinct aromatic

Usage

a. Synthesis of various organic compounds
b. Building block in pharmaceuticals and agrochemicals production
c. Versatile intermediate in organic chemistry

Unique structure

Useful for creating complex molecules with specific properties

Biological activity

Studied for potential as an anti-cancer agent

Hazardous properties

Can cause skin and eye irritation

Safety precautions

Handle and use with caution

Upstream product

• 52940-12-2 1,3,6,8-tetrahydroxy anthracene-9,10-dione 
• 922-69-0 1,1-dimethoxyethylene 
• 65565-47-1 2-bromo-6,8-dimethoxy-1,4-naphthoquinone 
• 695-99-8 2-Chloro-1,4-benzoquinone 
• 39828-35-8 2,4-dimethoxybenzoyl chloride 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 85565-93-1 2-bromo-3,5-dimethoxy-benzaldehyde 
• 142601-55-6 N,N-diethyl-2,4-dimethoxybenzamide 
• 36440-19-4 5,7-dimethoxy-1,4-naphthoquinone 
• 106875-55-2 (Z)-(1,3-dimethoxybuta-1,3-dienyloxy)trimethylsilane 
• 115066-15-4 5,7-dimethoxy-3-phenylsulfinyl-1,4-naphthoquinone 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 52940-12-2 1,3,6,8-tetrahydroxy anthracene-9,10-dione 

Relevant academic research and scientific papers

Total synthesis of topopyrones B and D

(Chemical Equation Presented) We describe a straightforward synthesis of topopyrones B and D, which are potent and selective inhibitors of topoisomerase I. The chemistry should be suitable for additional structure-activity relationship (SAR) work.

Utilization of Sulfide, Sulfoxide, and Sulfone Groups as Regiochemical Control Elements in the Diels-Alder Reaction of Naphthoquinones

The Diels-Alder reactions of 2-phenylthio-, 2-phenylsulfinyl-, and 2-phenylsulfonyl-1,4-naphthoquinones, which were unsymmetrically substituted by methoxyl group on the benzenoid ring, with some vinylketene acetals were studied.The regioselectively of the

Regioselective Bromination of 1,4-Naphthoquinones

1,4-Naphthoquinones unsymmetrically substituted in the benzenoid ring undergo bromination at the 2- and/or 3-positions.The isomeric composition of the products is strongly influenced by the conditions of bromination, addition of hydrogen bromide usefully complementing the conventional procedure involving addition of bromine.In favourable cases, involving methoxynaphthoquinones, these two procedures afford controlled access to individual 2- and 3- bromo derivatives.