24760-36-9

Basic information

• Product Name: 2-(2-THIENYLMETHYLENE)INDANE-1,3-DIONE
• Synonyms: 2-(2-THIENYLMETHYLENE)INDANE-1,3-DIONE;2-(2-THIENYLMETHYLENE)-1H-INDENE-1,3(2H)-DIONE;2-[(thiophen-2-yl)methylidene]-2,3-dihydro-1H-indene-1,3-dione
• CAS NO: 24760-36-9
• Molecular Formula: C₁₄H₈O₂S
• Molecular Weight: 240.28
• Mol File: 24760-36-9.mol
• Article Data: 14

Chemical Properties

• Melting Point: 177 °C
• Boiling Point: 440.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.423±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(2-THIENYLMETHYLENE)INDANE-1,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-THIENYLMETHYLENE)INDANE-1,3-DIONE(24760-36-9)
• EPA Substance Registry System: 2-(2-THIENYLMETHYLENE)INDANE-1,3-DIONE(24760-36-9)

Safety Data

• Hazardous Substances Data: 24760-36-9(Hazardous Substances Data)

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 606-23-5 1H-indene-1,3(2H)-dione 
• 1896-62-4 (E)-benzalacetone 

Downstream Products

• 1607832-16-5 (Z)-2-(2-oxo-2-phenyl-1-(thiophen-2-yl)ethylidene)-1H-indene-1,3(2H)-dione 
• 952720-99-9 C₂₆H₁₇N₃O₃S₂ 

Relevant articles and documents

Highly diastereoselective spiro-cyclopropanation of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides

A highly diastereoselective spiro-cyclopropanation reaction of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides has been developedviabase-induced annulation. This efficient and simple protocol features simple operations, mild conditions and excellent functional group compatibility. A variety of structurally interesting spiro-cyclopropanes were prepared in excellent yields and diastereomeric ratios (up to 97% yield and 20?:?1 dr). Also, ring expansion of the cyclopropanation product to quickly deliver a complex indeno[1,2-c]pyridazine structure showcased an interesting application of this method.

Rapid and selective synthesis of spiropyrazolines and pyrazolylphthalides employing Seyferth-Gilbert reagent

An unexpected product-selectivity in the reaction of 2-arylideneindane-1,3-dione with dimethyl diazomethylphosphonate leading to the formation of two different types of products is reported. The reaction carried out in acetone in the presence of catalytic amount of cesium fluoride afforded spiropyrazoline phosphonates via 1,3-dipolar cycloaddition reaction, whereas the reaction in methanol yielded an interesting class of pyrazolylphthalides. This strategy provides an efficient alternative method for the construction of pyrazolylphthalides, and moreover, the process is general, works under mild conditions, and exhibits high functional group compatibility.

Direct β-acylation of 2-arylidene-1,3-indandiones with acyl chlorides catalyzed by organophosphanes

We have developed an organophosphane-catalyzed direct β-acylation of a series of conjugated systems bearing ketone, amide and ester functionalities using acyl chlorides as trapping reagents. A wide variety of highly functional ketone derivatives were gene