24767-67-7Relevant articles and documents
Iridium-catalyzed 1,3-hydrogen shift/chlorination of allylic alcohols
Ahlsten, Nanna,Gomez, Antonio Bermejo,Martin-Matute, Belen
supporting information, p. 6273 - 6276 (2013/07/05)
Tandem: Allylic alcohols react with N-chlorosuccinimide (NCS) in a tandem 1,3-H shift/C-Cl bond formation leading to α-chloroketones and α-chloroaldehydes. The reactions proceed with complete selectivity to give single constitutional isomers of monochlorinated carbonyl compounds. The utility of the transformation is illustrated by the straightforward synthesis of 4,5-disubstituted 2-aminothiazoles from allylic alcohols. Copyright
One-Pot Synthesis of α-Chloro Ketones from Secondary Alcohols Using N,N-Dichloro-p-toluenesulfonamide
Kim, Yong Hae,Lee, In Sang,Lim, Sang Chul
, p. 1125 - 1128 (2007/10/02)
Various alkyl aryl secondary alcohols reacted with N,N-dichloro-p-toluenesulfonamide (N,N-dichloroamine-T) in CH3CN at 35 deg C to give the corresponding α-chloro ketones in excellent yields under mild and neutral conditions.
Metal-Catalyzed Organic Photoreactions. One-Step Synthesis of Chlorinated Ketones from Olefins by Photooxidation in the Presence of Iron(III) Chloride
Kohda, Akira,Ueda, Keiko,,Sato, Tadashi
, p. 509 - 515 (2007/10/02)
Under photooxidation in pyridine in the presence of FeCl3, mono- and disubstituted olefins gave α-chloro ketones, while tri- and tetrasubstituted olefins gave dichloro ketones with a C-C bond cleavage.The reaction was interpreted in terms of an electron-transfer mechanism occurring within the coordination sphere of the iron ion