2478-67-3

Usage

Chemical class

Anthracenedione derivative

Functional groups

a. Amino group (-NH2)
b. Chloro group (-Cl)
c. Hydroxy group (-OH)

Structural properties

a. Aromatic ring system
b. Quinone core
c. Substitution at positions 1, 2, and 4

Applications

a. Synthetic intermediate in pharmaceutical production
b. Organic compound synthesis

Potential uses

a. Medicinal chemistry
b. Drug development
c. Research in biological and chemical processes

InChI:InChI=1/C14H8ClNO3/c15-8-5-9(17)10-11(12(8)16)14(19)7-4-2-1-3-6(7)13(10)18/h1-5,17H,16H2

Upstream product

• 7664-93-9 sulfuric acid 
• 13432-32-1 1-amino-2,4-dichloroanthraquinone 
• 50981-12-9 sulfuric acid monohydrate 
• 104-88-1 4-chlorobenzaldehyde 
• 82-45-1 1-amino-9,10-anthracenedione 
• 757129-66-1 2-(5-amino-2,4-dichloro-benzoyl)-benzoic acid 

Downstream Products

• 105551-27-7 1-amino-2-(4-fluorophenoxy)-4-hydroxyanthraquinone 
• 105551-28-8 1-amino-2-(2,4,6-trimethylphenoxy)-4-hydroxyanthraquinone 
• 54243-60-6 1-amino-2-(4-methoxyphenoxy)-4-hydroxyanthraquinone 
• 17869-07-7 1-amino-4-hydroxy-2-(2'-hydroxyethoxy)-anthraquinone 
• 23753-49-3 1-amino-4-hydroxy-2-(2'-phenylethoxy)-anthraquinone 
• 116-85-8 4-hydroxy-1-aminoanthraquinone 
• 105551-31-3 1-azido-2-(2,4,6-trimethylphenoxy)-4-hydroxyanthraquinone 
• 105551-30-2 1-azido-2-(4-methoxyphenoxy)-4-hydroxyanthraquinone 
• 105551-34-6 3-(2,4,6-trimethylphenoxy)-5-hydroxyanthra<1,9-cd>-6-isoxazolone 
• 105551-29-9 1-azido-2-(4-fluorophenoxy)-4-hydroxyanthraquinone 
• 105551-33-5 5-Hydroxy-3-(4-methoxy-phenoxy)-anthra[1,9-cd]isoxazol-6-one 
• 105551-32-4 3-(4-Fluoro-phenoxy)-5-hydroxy-anthra[1,9-cd]isoxazol-6-one 
• 38912-97-9 N-[5-(1-Amino-4-hydroxy-9,10-dioxo-9,10-dihydro-anthracen-2-yloxy)-2-methyl-phenyl]-acetamide 

Relevant academic research and scientific papers

Process for the preparation of a mixture of 1-amino-2-chloro-4-hydroxyanthraquinone and 1-amino-2-bromo-4-hydroxyanthraquinone

A process for the preparation of a mixture of 1-amino-2-chloro-4-hydroxyanthraquinone and 1-amino-2-bromo-4-hydroxyanthraquinone, which mixture contains a high proportion of 1-amino-2-chloro-4-hydroxyanthraquinone, by chlorinating and brominating 1-aminoanthraquinone and reacting the intermediate so obtained with concentrated or fuming sulfuric acid.

Process for the preparation of aromatic hydroxy compounds

The invention relates to a process for the preparation of aromatic hydroxy compounds, starting from the corresponding halogenated aromatic compounds and replacing the halogen atom or atoms by the hydroxyl group. The process comprises converting the halogenated aromatic compound into the hydroxy compound by treatment with concentrated sulfuric acid, with the addition of an aldehyde and at elevated temperature. The aromatic hydroxy compounds are used as intermediates, for example for the manufacture of disperse and vat dyes.