24782-66-9

Basic information

• Product Name: 5-Methyl-9-oxo-9,10-dihydroacridine-4-carboxylic acid
• Synonyms: 5-Methyl-9-oxo-9,10-dihydroacridine-4-carboxylic acid
• CAS NO: 24782-66-9
• Molecular Formula: C₁₅H₁₁NO₃
• Molecular Weight: 253.25274
• Mol File: 24782-66-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 358-368 °C
• Boiling Point: 481.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.351±0.06 g/cm3(Predicted)
• PKA: 3.32±0.20(Predicted)
• CAS DataBase Reference: 5-Methyl-9-oxo-9,10-dihydroacridine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-9-oxo-9,10-dihydroacridine-4-carboxylic acid(24782-66-9)
• EPA Substance Registry System: 5-Methyl-9-oxo-9,10-dihydroacridine-4-carboxylic acid(24782-66-9)

Safety Data

• Hazardous Substances Data: 24782-66-9(Hazardous Substances Data)

Upstream product

• 95-53-4 o-toluidine 
• 39622-79-2 2-aminoisophthalic acid 
• 4389-45-1 3-methylantranilic acid 
• 2902-65-0 2-iodoyl-1,3-benzenedicarboxylic acid 
• 118-91-2 ortho-chlorobenzoic acid 
• 59425-36-4 3-methylanthranilic acid potassium salt 
• 80841-45-8 2-<(2-carboxyphenyl)amino>-3-methylbenzoic acid 
• 98370-26-4 2-N-(2-methylphenyl) aminoisophthalic acid 

Downstream Products

• 92138-16-4 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-5-methyl-acridine-4-carboxylic acid methylamide; hydrochloride 
• 89459-51-8 9-Amino-5-methyl-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 106626-72-6 5-Methyl-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide 

Relevant articles and documents

Anticancer anilinoacridines. A process synthesis of the disubstituted amsacrine analog CI-921

An improved process for the synthesis of bulk quantities of the clinical amsacrine analog CI-921 is reported. Described also are detailed analytical and spectroscopic data for this agent.

The Synthesis of Substituted 9-Oxoacridan-4-carboxylic Acids; Part 2. The Use of 2-Iodoisophthalic Acid in the Jourdan-Ullmann Reaction

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Compound having antitumor properties

The compound 4'-(9-[4-[N-methyl-carboxamido]-5-methyl]acridinylamino)methanesulphon-m-anisidide and acid addition salts thereof have antitumor properties.