80841-45-8

Upstream product

• 4389-45-1 3-methylantranilic acid 
• 118-91-2 ortho-chlorobenzoic acid 
• 59425-36-4 3-methylanthranilic acid potassium salt 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 80841-44-7 potassium 3-methyl-2-nitrobenzoate 
• 584-08-7 potassium carbonate 
• 7440-44-0 pyrographite 

Downstream Products

• 24782-66-9 9,10-dihydro-5-methyl-9-oxo-4-acridinecarboxylic acid 
• 88377-20-2 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-5-methyl-acridine-4-carboxylic acid amide; hydrochloride 
• 92138-16-4 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-5-methyl-acridine-4-carboxylic acid methylamide; hydrochloride 

Relevant academic research and scientific papers

Anticancer anilinoacridines. A process synthesis of the disubstituted amsacrine analog CI-921

An improved process for the synthesis of bulk quantities of the clinical amsacrine analog CI-921 is reported. Described also are detailed analytical and spectroscopic data for this agent.

Potential antitumor agents. 40. Orally active 4,5-disubstituted derivatives of amsacrine

The DNA-intercalating agent amsacrine is an effective drug for the treatment of human leukemias and lymphomas but has minimal solid tumor activity. As a first step in identifying analogues with a wider spectrum of activity, a comparison was made of the in

Compound having antitumor properties

The compound 4'-(9-[4-[N-methyl-carboxamido]-5-methyl]acridinylamino)methanesulphon-m-anisidide and acid addition salts thereof have antitumor properties.

Novel aminobenzoic acid derivatives, process for preparing the same and pharmaceutical composition containing the same

An aminobenzoic acid derivative represented by the formula STR1 wherein R1, R2 and R3 are defined hereinbelow, which has excellent activity for improving liver function and for potentiating and normalizing immunity; a process for preparing the same; and a pharmaceutical composition containing the same are disclosed.