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24815-24-5

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Product FOB Price Min.Order Supply Ability Supplier
Natural Extract 98% RESCINNAMINE 24815-24-5 HACCP Manufacturer
Cas No: 24815-24-5
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Yohimban-16-carboxylicacid,11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]oxy]-,methyl ester, (3b,16b,17a,18b,20a)-
Cas No: 24815-24-5
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
24815-24-5 RESCINNAMINE
Cas No: 24815-24-5
USD $ 8900.0-8900.0 / Kilogram 1 Kilogram 20000 Kilogram/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
Yohimban-16-carboxylicacid,11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]oxy]-,methyl ester, (3b,16b,17a,18b,20a)-
Cas No: 24815-24-5
No Data No Data 10000 Metric Ton/Month Henan Wentao Chemical Product Co., Ltd. Contact Supplier
Yohimban-16-carboxylicacid,11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]oxy]-,methyl ester, (3b,16b,17a,18b,20a)-
Cas No: 24815-24-5
No Data 1 Gram 10000 Metric Ton/Month Shanghai Upbio Tech Co.,Ltd Contact Supplier
Supply Rescinnamine CAS 24815-24-5
Cas No: 24815-24-5
USD $ 130.0-140.0 / Kilogram 1 Kilogram 100 Kilogram/Month XI'AN JUNYUAN BIO-TECH CO., LTD. Contact Supplier
Yohimban-16-carboxylicacid,11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]oxy]-,methyl ester, (3b,16b,17a,18b,20a)-
Cas No: 24815-24-5
No Data No Data 5 Hangzhou J&H Chemical Co., Ltd. Contact Supplier
Rescinnamine CAS NO.24815-24-5
Cas No: 24815-24-5
No Data 10 Gram 500 Kilogram/Week Zibo Hangyu Import&Export Co., Ltd Contact Supplier
High quality Rescinnamine
Cas No: 24815-24-5
No Data 1 Kilogram 2000 Metric Ton/Year Xiamen BaiFuchem Co.,Ltd Contact Supplier
RESCINNAMINE
Cas No: 24815-24-5
No Data 1 Milligram 5 Xiamen Jenny Chemical Technology Co., Ltd. Contact Supplier

24815-24-5 Usage

Description

This Rauwolfia alkaloid is found in the barks of R. serpentina and R. vomitora and was originally given the name Reserpinine, this being altered to avoid confusion with another alkaloid of the same name (q.v.). The base has [α]17D - 99.2° (c 1.3, CHCI3). From chemical degradation and spectroscopic analysis, the structure has been established as the 3:4: 5-trimethoxycinnamoyl ester of reserpic acid.

Chemical Properties

white to cream powder

Uses

Rescinnamine occurs in the roots of a num ber of Rauwolfia species. Therapeutically, itis used as an antihypertensive agent.

Uses

Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.

Brand name

Moderil (Pfizer).

General Description

Odorless white to cream colored crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

The neat material darkens slowly on exposure to light. In solution this occurs more rapidly. .

Health Hazard

The pharmacological properties of rescinnamine are similar to those of reserpine, butthe side effects are low. It acts as a sedativeand hypotensive. A dose of 0.25 mg/day mayproduce the effect of sleepiness in humans.Excessive doses may produce depression,nightmare, nausea, diarrhea, and hypotension.LD50 value, oral (rats): 1000 mg/kgThe carcinogenicity of rescinnamine inanimals or humans is unknown.

Fire Hazard

Flash point data for RESCINNAMINE are not available. RESCINNAMINE is probably combustible.

Purification Methods

Crystallise it from *benzene, MeOH or aqueous Me2CO. The hydrochloride has m 232o(dec) (from MeOH) and [] D -74o (MeOH). It is an antihypertensive. [Klohs et al. J Am Chem Soc 77 2241 1955, Beilstein 25 III/IV 1323.]

References

Haack e tal., Naturwiss., 41, 214 (1954) Klohs, Draper, Keller.,J. Amer. Chem. Soc., 77,2241 (1955) Kidd., Chem. & Ind., 1481 (1955) Popelak, Lettenbauer., Arch. Pharm., 296,261 (1963)
InChI:InChI=1/C35H42N2O9/c1-40-21-8-9-22-23-11-12-37-18-20-15-29(46-30(38)10-7-19-13-27(41-2)33(43-4)28(14-19)42-3)34(44-5)31(35(39)45-6)24(20)17-26(37)32(23)36-25(22)16-21/h7-10,13-14,16,20,24,26,29,31,34,36H,11-12,15,17-18H2,1-6H3/b10-7+/t20-,24+,26-,29-,31+,34+/m1/s1

24815-24-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name rescinnamine

1.2 Other means of identification

Product number -
Other names Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]oxy]-, methyl ester, (3β,16β,17α,18β,20α)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24815-24-5 SDS

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