Products Categories
CAS No.: | 24815-24-5 |
---|---|
Name: | RESCINNAMINE |
Article Data: | 6 |
Molecular Structure: | |
Formula: | C35H42 N2 O9 |
Molecular Weight: | 634.726 |
Synonyms: | 3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate(ester) (8CI); Rescinnamine (6CI); Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]oxy]-,methyl ester, (3b,16b,17a,18b,20a)- (9CI);Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.;3,4,5-Trimethoxycinnamoyl methyl reserpate; Anaprel; Apoterin; Apoterin S;Cartric; Cinnaloid; Methyl trimethoxycinnamoylreserpate; Moderil; NSC 15628;O-(3,4,5-Trimethoxy-trans-cinnamoyl) methyl reserpate; Rescinnamin; Rescisan;Resealoid; Reserpic acid methyl ester 3,4,5-trimethoxycinnamate; Reserpinine;Reserpinine (C35 alkaloid); Scinnamina |
EINECS: | 246-471-8 |
Density: | 1.31g/cm3 |
Melting Point: | 238 C |
Boiling Point: | 756.8°C at 760 mmHg |
Flash Point: | 411.5°C |
Solubility: | Toxicity data ">
negligible
Stability
Toxicology
Toxicity data |
Appearance: | white to cream powder |
Hazard Symbols: | Xn |
Risk Codes: | 25-20/21/22 |
Safety: | Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: olfactory changes, somnolence, and antipsychotic effects. Experimental reproductive effects. When heated to decomposition it emits toxic NOx. |
PSA: | 117.78000 |
LogP: | 4.50860 |
The Synonyms name of Rescinnamine (CAS NO.24815-24-5): 11,17alpha-Dimethoxy-18beta-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-3beta,20alpha-yohimban-16beta-carboxylic acid methyl ester ; 3,4,5-Trimethoxycinnamic acid, methyl reserpate ; 3,4,5-Trimethoxycinnamoyl methyl reserpate ; 3,4,5-Trimethylcinnamic acid, ester with methyl reserpate ; 3,4,5-Trimethylcinnamoyl methyl reserpate ; 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-Hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-
trimethoxycinnamate (ester), (E)- ; 4-25-00-01323 (Beilstein Handbook Reference) ; AI3-52763 ; Anaprel ; Apolon ; Apoterin ; BRN 0075328 ; CCRIS 4711 ; Cartric ; Cinamine ; Cinatabs ; Cinnaloid ; Cinnasil ; HSDB 2176 ; Methyl 18-O-(3,4,5-trimethoxycinnamoyl)reserpate ;Methyl ; 1alpha,2beta,3alpha,4,4aalpha,5,7,8,13,13bbeta,14,14aalpha-dodecahydro-2alpha,11-dimethoxy-3beta-(3,4,5-trimethoxycinnamoyloxy)benz(g)indolo(2,3-a)quinolizine-1beta-carboxylate ; Methyl reserpate 3,4,5-trimethoxycinnamic acid ester ; Methyl trimethoxycinnamoylreserpate ; Moderil ; NSC 15628 ; Normorescina ; Paresinan ; Raupyrol ; Raurescin ;Raurescine ; Recinnamine ; Recitensina ; Rescaloid ; Rescamin ; Rescidan ; Rescin ; Rescinamina ; Rescinnaminum [INN-Latin] ; Rescinpal ; Scinnamina ; Tenamine ; Trimethoxy cinnamoyl reserpate de methyl ; Trimethoxy cinnamoyl reserpate de methyl [French] ; Trimethoxycinnamoyl methyl reserpate ; Tuareg ; Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-oxy)-, methyl ester,(3beta,16beta,17alpha,18beta(E),20alpha
CAS: 24815-24-5
EINECS: 246-471-8
Molecular Formula: C35H42N2O9
Formula Weight: 634.72 g/mol
Molecular Structure:
Index of Refraction: 1.621
Density: 1.31 g/cm3
Flash Point: 411.5 °C
Boiling Point: 756.8 °C at 760 mmHg
Chemical Properties: white to cream powder
General Description: Odorless white to cream colored crystalline powder.
Air & Water: Reactions Insoluble in water.
The toxicity of Rescinnamine (CAS NO.24815-24-5):
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LDLo | intravenous | 35mg/kg (35mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 600, 1973. | |
human | TDLo | oral | 4ug/kg/D (0.004mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ANTIPSYCHOTIC | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 517, 1969. |
mouse | LD50 | intraperitoneal | 65mg/kg (65mg/kg) | French Medicament Patent Document. Vol. #5226M, | |
mouse | LD50 | intravenous | 56mg/kg (56mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00965, | |
mouse | LD50 | oral | 1420mg/kg (1420mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 109, 1972. | |
mouse | LD50 | subcutaneous | 263mg/kg (263mg/kg) | French Medicament Patent Document. Vol. #5226M, | |
rat | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | Drugs in Japan Vol. 6, Pg. 898, 1982. | |
rat | LD50 | oral | 1gm/kg (1000mg/kg) | Drugs in Japan Vol. 6, Pg. 898, 1982. | |
rat | LD50 | subcutaneous | 540mg/kg (540mg/kg) | Drugs in Japan Vol. 6, Pg. 898, 1982. |
The Risk Statements of Rescinnamine (CAS NO.24815-24-5):R25 :Toxic if swallowed.
Safety Statements: S22:Do not breathe dust. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 1544
HazardClass: 6.1(b)
PackingGroup: III
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: olfactory changes, somnolence, and antipsychotic effects. Experimental reproductive effects. When heated to decomposition it emits toxic NOx.