248248-99-9

Upstream product

• 197229-98-4 5-ethyl-2-methoxy-6-methyl-3-pivaloylaminopyridine 
• 5779-95-3 3,5-dimethylbenzaldehyde 
• 108-24-7 acetic anhydride 
• 248248-98-8 N-[5-ethyl-2-methoxy-6-methyl-4-(3,5-dimethylbenzoyl)pyridin-3-yl]-2,2-dimethylpropionamide 

Downstream Products

• 311319-92-3 {[4-(3,5-dimethyl-benzyl)-5-ethyl-6-methyl-2-oxo-1,2-dihydro-pyridin-3-ylcarbamoyl]-methyl}-carbamic acid tert-butyl ester 
• 311319-88-7 N-[4-(3,5-dimethyl-benzyl)-5-ethyl-6-methyl-2-oxo-1,2-dihydro-pyridin-3-yl]-propionamide 
• 311319-89-8 N-[4-(3,5-dimethyl-benzyl)-5-ethyl-6-methyl-2-oxo-1,2-dihydro-pyridin-3-yl]-acetamide 
• 311319-90-1 N-[4-(3,5-dimethyl-benzyl)-5-ethyl-6-methyl-2-oxo-1,2-dihydro-pyridin-3-yl]-formamide 
• 248247-37-2 4-(3,5-dimethyl-benzyl)-5-ethyl-6-methyl-3-methylamino-1H-pyridin-2-one 
• 248246-95-9 3-amino-4-(3,5-dimethylbenzyl)-5-ethyl-6-methylpyridin-2(1H)-one 
• 248248-97-7 4-(3,5-dimethylbenzyl)-5-ethyl-2-methoxy-6-methyl-3-pivaloylaminopyridine 

Relevant academic research and scientific papers

Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors

Several 4-benzyl analogues of 5-ethyl-6-methyl-4-(phenylthio)pyridin-2(1H)-ones were synthesized and evaluated for their anti-HIV-1 activities. Key transformations include metalation at the 4-C-position of 5-ethyl-2-methoxy-6-methyl-3-pivaloylaminopyridin