248250-13-7

Upstream product

• 248250-10-4 9-[(tert-butyl)(diphenyl)silanyloxy]-4,4-dimethylnona-5,7-dien-1-ol 
• 248250-11-5 (5E,7E)-9-(tert-Butyl-diphenyl-silanyloxy)-4,4-dimethyl-nona-5,7-dienal 
• 248250-09-1 tert-Butyl-((2E,4E)-6,6-dimethyl-nona-2,4,8-trienyloxy)-diphenyl-silane 
• 248250-07-9 (2E,4E)-6,6-Dimethyl-nona-2,4,8-trienoic acid methyl ester 
• 248250-08-0 (2E,4E)-6,6-dimethyl-2,4,8-nonatrien-1-ol 
• 5497-67-6 2,2-dimethyl-4-pentenal 
• 248250-12-6 (S)-3-[(5E,7E)-(R)-9-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxy-4,4-dimethyl-nona-5,7-dienyl]-5-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-5H-furan-2-one 

Downstream Products

• 303780-20-3 (3S,3aS,4S,6aS,10aR)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-3a,4,6a,7,8,9-hexahydro-3H-2-oxa-cyclopenta[d]naphthalene-1,10-dione 
• 329897-84-9 (3S,3aS,4S,6aS,10aR)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-3,3a,4,6a,7,8-hexahydro-2-oxa-cyclopenta[d]naphthalen-1-one 
• 303780-21-4 (3S,3aS,4S,6aS,10aR)-4-Hydroxymethyl-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-3a,4,6a,7,8,9-hexahydro-3H-2-oxa-cyclopenta[d]naphthalene-1,10-dione 
• 329897-86-1 (3S,3aS,4S,6aS,10aR)-4-Hydroxymethyl-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-3,3a,4,6a,7,8-hexahydro-2-oxa-cyclopenta[d]naphthalen-1-one 
• 329897-87-2 (3S,3aS,6aS,10aR)-3-((1S,2R,5S)-2-Isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8-hexahydro-2-oxa-cyclopenta[d]naphthalene-4-carbaldehyde 
• 330998-92-0 4-Nitro-benzoic acid (3S,3aS,4S,6aS,10S,10aR)-4-(tert-butyl-diphenyl-silanyloxymethyl)-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-1-oxo-3,3a,4,6a,7,8,9,10-octahydro-2-oxa-cyclopenta[d]naphthalen-10-yl ester 
• 330998-91-9 (3S,3aS,4S,6aS,10S,10aR)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-10-hydroxy-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-3,3a,4,6a,7,8,9,10-octahydro-2-oxa-cyclopenta[d]naphthalen-1-one 
• 330998-94-2 4-Nitro-benzoic acid (3S,3aS,6aS,10S,10aR)-4-formyl-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8,9,10-octahydro-2-oxa-cyclopenta[d]naphthalen-10-yl ester 
• 330998-93-1 4-Nitro-benzoic acid (3S,3aS,4S,6aS,10S,10aR)-4-hydroxymethyl-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-1-oxo-3,3a,4,6a,7,8,9,10-octahydro-2-oxa-cyclopenta[d]naphthalen-10-yl ester 
• 330998-95-3 (3S,3aS,6aS,10S,10aR)-10-Hydroxy-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-1-oxo-3,3a,6,6a,7,8,9,10-octahydro-2-oxa-cyclopenta[d]naphthalene-4-carbaldehyde 
• 158761-03-6 mniopetal F 
• 329897-85-0 Trifluoro-methanesulfonic acid (3S,3aS,4S,6aS,10R,10aR)-4-(tert-butyl-diphenyl-silanyloxymethyl)-3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-7,7-dimethyl-1-oxo-3,3a,4,6a,7,8,9,10-octahydro-2-oxa-cyclopenta[d]naphthalen-10-yl ester 

Relevant academic research and scientific papers

Synthetic studies towards mniopetals (II). A short synthesis of Mniopetal E

A short total synthesis of Mniopetal E in thirteen steps is reported. Key steps are a new and highly diastereoselective lithium phenylselenide induced Baylis-Hillman reaction with Feringa's butenolide, an endo-selective intramolecular Diels-Alder reaction (IMDA) and a new variant of the Parikh-Doering oxidation.

A short synthesis of Mniopetal F?

The first total synthesis of Mniopetal F in fourteen steps is reported. Key steps are a new and highly diastereoselective lithium phenylselenide-induced Baylis-Hillman reaction with Feringa's butenolide, an endo-selective intramolecular Diels-Alder reaction (IMDA), inversion of a highly hindered secondary alcohol and a new variant of the Parikh-Doering oxidation.

Intramolecular Diels-Alder reactions with substituted Feringa-butenolides: a dramatic increase in reactivity by double activation

A thermal intramolecular endo-selective Diels-Alder reaction with a substituted Feringa-butenolide is described. The structure of the main product is determined by single crystal X-ray analysis. By double activation of the dienophile substructure a dramatic increase in reactivity is reported, which leads to a decrease in reaction temperature by more than 100°C. Copyright (C) 2000 Elsevier Science Ltd.

A short total synthesis of kuehneromycin A

Only eleven steps were needed to synthesize kuehneromycin A (1) which inhibits reverse transcriptase (see picture). Key steps are a new variant of the Baylis-Hillman reaction, an endo-selective intramolecular Diels - Alder reaction, and a new protocol for

Synthetic studies towards mniopetals (I). A short synthesis of a key intermediate for the total synthesis of mniopetals

A short and efficient synthesis of a tricyclic core structure of mniopetals based on a new, highly diastereoselective PhSeLi induced Baylis- Hillman reaction and an endo-selective Intramolecular Diels-Alder reaction (IMDA) as key steps is presented.