24845-06-5Relevant academic research and scientific papers
Facile synthesis of 1,2-thiobenzonitriles: Via Cu-catalyzed denitrogenative radical coupling reaction
Zhou, Yao,Wang, Ya,Lou, Yixian,Song, Qiuling
, p. 10265 - 10268 (2019)
A Cu-catalyzed synthesis of 1,2-thiobenzonitriles via oxidative C-N cleavage of 3-aminoindazoles followed by radical coupling with thiols is developed. A diverse array of 1,2-thiobenzonitriles were obtained in good yields with wide substrate scope. Notably, this is the first example of denitrogenative radical coupling with 3-aminoindazoles.
